Background Currently, there is no formally accepted pharmacological treatment for COVID-19. Materials and methods We included COVID-19 outpatients of a Peruvian primary care center from Lima, Peru, who were treated between April 30 - September 30, 2020, with hydroxychloroquine and azithromycin. Logistic regression was applied to determine factors associated with case-fatality rate. Results A total of 1265 COVID-19 patients with an average age of 44.5 years were studied. Women represented 50.1% of patients, with an overall 5.9 symptom days, SpO2 97%, temperature of 37.3 °C, 41% with at least one comorbidity and 96.1% one symptom or sign. No patient treated within the first 72 h of illness died. The factors associated with higher case fatality rate were age (OR = 1.06; 95% CI 1.01–1.11, p = 0.021), SpO2 (OR = 0.87; 95% CI 0.79–0.96, p = 0.005) and treatment onset (OR = 1.16; 95% CI 1.06–1.27, p = 0.002), being the latter the only associated in the multivariate analysis (OR = 1.18; 95% CI 1.05–1.32, p = 0.005). 0.6% of our patients died. Conclusions The case fatality rate in COVID-19 outpatients treated with hydroxychloroquine/azithromycin was associated with the number of days of illness on which treatment was started.

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Objetivo: Describir los diferentes elementos psico-espirituales en pacientes con cáncer aplicando la escala Functional Assessment of Chronic Illness Therapy - Spiritual Well Being, FACIT-Sp (Evaluación Funcional de Terapia de Enfermedades Crónicas y Bienestar Espiritual). Métodos: Aplicación de la escala a una muestra de pacientes (n = 100) con diagnóstico de cáncer, estadio IV, del Servicio de Oncología del Hospital Nacional Arzobispo Loayza. El instrumento de 33 preguntas examina cinco áreas: bienestar social (SWB), bienestar emocional (EWB), bienestar funcional (FWB), sentido y paz (MP) y fe (F). Resultados: En la muestra estudiada, el aspecto más resaltante fue el relacionado con F (puntaje promedio=13,53 ± 3,05, correspondiente al 84,56% del puntaje máximo posible) y el más bajo fue el vinculado a FWB (puntaje promedio=15,79 ± 6,89, correspondiente al 56,39% del puntaje máximo posible). Conclusiones: De acuerdo a FACIT-Sp, el aspecto psico-espiritual más desarrollado en los pacientes de la muestra estudiada fue el relativo a la Fe y el menos desarrollado, el vinculado al área de Bienestar Funcional.