The induced gravitational collapse (IGC) paradigm of long gamma-ray bursts (GRBs) associated with supernovae (SNe) predicts a copious neutrino-antineutrino (νν) emission owing to the hypercritical accretion process of SN ejecta onto a neutron star (NS) binary companion. The neutrino emission can reach luminosities of up to 10 57 MeV s −1 , mean neutrino energies 20 MeV, and neutrino densities 10 31 cm −3 . Along their path from the vicinity of the NS surface outward, such neutrinos experience flavor transformations dictated by the neutrino to electron density ratio. We determine the neutrino and electron on the accretion zone and use them to compute the neutrino flavor evolution. For normal and inverted neutrino-mass hierarchies and within the two-flavor formalism (ν e ν x ), we estimate the final electronic and non-electronic neutrino content after two oscillation processes: (1) neutrino collective effects due to neutrino self-interactions where the neutrino density dominates and, (2) the Mikheyev-Smirnov-Wolfenstein (MSW) effect, where the electron density dominates. We find that the final neutrino content is composed by ∼55% (∼62%) of electronic neutrinos, i.e. ν e +ν e , for the normal (inverted) neutrino-mass hierarchy. The results of this work are the first step toward the characterization of a novel source of astrophysical MeV-neutrinos in addition to core-collapse SNe and, as such, deserve further attention.

Introduction: A cerebrospinal fluid (CSF) shunt is the primary treatment for most etiologies of hydrocephalus in the pediatric population. Malfunction of the shunt may present with unique symptoms and signs. This retrospective review investigates the presenting signs and symptoms of pediatric patients with shunt malfunction. Clinical Material and Method: One-hundred-and-thirty CSF diversion procedures were performed at two affiliated pediatric hospitals over a 2-year period. Seventy consecutive cases of CSF shunt revision were reviewed. These 70 operations were performed on 65 patients. Their medical records and radiographic studies were reviewed, and supplemented with a telephone interview to obtain a minimum of 3 months follow-up. Results: The 65 patients’ age ranged from 3 months to 16 years. The original etiology of the hydrocephalus was Chiari II malformation in 17, idiopathic in 15 and intraventricular hemorrhage in 10, neoplasm in 8 patients and meningitis in 5 patients. The most frequent presenting symptoms were headache (39 admissions), nausea/vomiting (28) and drowsiness (21). Seven Chiari patients (41%) presented with neck pain, 2 (12%) presented with lower cranial nerve palsy, and 2 (12%) presented with symptomatic syrinx, complaints not reported by non-Chiari patients (p < 0.01, χ² analysis). Four myelodysplastic patients presented with a new-onset or recurrent seizure episode, which was significantly more frequent than in nonmyelodysplastic patients (p < 0.05, χ² analysis). On examination, increased head circumference was noted in 17 patients. Parinaud’s syndrome was noted more prominently in patients with a history of intracranial neoplasm (4 of 8 cases) than in patients with nonneoplastic diseases (2 of 62 cases; p < 0.05, χ² analysis). Other interesting presenting signs were pseudocyst (2), syringomyelia (2), hemiparesis (2) and Parkinson-like rigidity (2). Conclusion: Pediatric shunt malfunction generally presents with headache, nausea/vomiting, altered mental status, increased head circumference and bulging fontanelle. Other less frequent but unique presenting signs and symptoms, such as neck pain, syringomyelia and lower cranial nerve palsy in the myelodysplastic population, and Parinaud’s syndrome in patients with a history of intracranial neoplasm are frequently associated with shunt malfunction and should prompt a radiographic workup.

Better understanding of how pneumocephalus displaces subcortical structures can significantly enhance our intraoperative decision making and overall targeting strategy.