This work investigates Industry 4.0 technologies by developing a new key performance indicator that can determine the energy consumption of machine tools for a more sustainable supply chain. To achieve this, we integrated the machine tool indicator into a cyber–physical system for easy and real-time capturing of data. We also developed software that can turn these data into relevant information (using Python): Using this software, we were able to view machine tool activities and energy consumption in real time, which allowed us to determine the activities with greater energy burdens. As such, we were able to improve the application of Industry 4.0 in machine tools by allowing informed real-time decisions that can reduce energy consumption. In this research, a new Key Performance Indicator (KPI) was been developed and calculated in real time. This KPI can be monitored, can measure the sustainability of machining processes in a green supply chain (GSC) using Nakajima’s six big losses from the perspective of energy consumption, and is able to detect what the biggest energy loss is. This research was implemented in a cyber–physical system typical of Industry 4.0 to demonstrate its applicability in real processes. Other productivity KPIs were implemented in order to compare efficiency and sustainability, highlighting the importance of paying attention to both terms at the same time, given that the improvement of one does not imply the improvement of the other, as our results show.

The purpose of this work is to develop a new Key Performance Indicator (KPI) that can quantify the cost of Six Big Losses developed by Nakajima and implements it in a Cyber Physical System (CPS), achieving a real-time monitorization of the KPI. This paper follows the methodology explained below. A cost model has been used to accurately develop this indicator together with the Six Big Losses description. At the same time, the machine tool has been integrated into a CPS, enhancing the real-time data acquisition, using the Industry 4.0 technologies. Once the KPI has been defined, we have developed the software that can turn these real-time data into relevant information (using Python) through the calculation of our indicator. Finally, we have carried out a case of study showing our new KPI results and comparing them to other indicators related with the Six Big Losses but in different dimensions. As a result, our research quantifies economically the Six Big Losses, enhances the detection of the bigger ones to improve them, and enlightens the importance of paying attention to different dimensions, mainly, the productive, sustainable, and economic at the same time.

No abstract

We have obtained, not only an overview of what is working (or not) from the view of adolescents and experts, but also the key points that should be taken into account for designing effective prevention policies.

Industry 4.0 is changing the industrial environment. Particularly, the emerging Industry 4.0 technologies can improve the agri-food supply chain throughout all its stages. This study aims to highlight the benefits of implementing Industry 4.0 in the agri-food supply chain. First, it presents how technologies enhance the agri-food supply chain development. Then, it identifies and highlights the most common challenges that Industry 4.0 implementation faces in agri-food’s environment. After that, it proposes key performance indicators to measure the advantages of this implementation. To achieve this, a systematic literature review was conducted. It combined conceptual and bibliometric analyses of 78 papers. As a result, the most suitable technologies were identified, e.g., Internet of Things, Big Data, blockchain and cyber physical systems. The most used indicators are proposed and the challenges of implementation were detected and classified in three groups, i.e., technical, educational and governmental. This paper highlights and exemplifies the benefits of implementing Industry 4.0 facing the lack of knowledge that exists nowadays. Moreover, it fulfils the gaps in literature, i.e., the lack of information about the implementation of technologies 4.0 or the description of the most relevant indicators for Industry 4.0 implementation.

No abstract

A detailed study of gametes development and characterization of plasma sex steroid hormones during the maturation cycle was performed for the first time in the southern hake (Merluccius australis). Fish were caught in the inland waters of the Reloncaví Sound, Interior Sea of Chiloé, Chile. Samples of gonads and blood were collected for histology and sex steroid hormone (17 β-estradiol, 11-ketotestosterone and 17,20 βdihydroxy-4-pregnen-3-one) analysis, respectively. Sex steroid hormone quantification was performed using enzyme-immunoassay (ELISA). Results showed that M. australis males and females have asynchronous development of testicles and ovaries, in all stages of maturation. Most spawning fish were found during the spring months. Regarding the sex steroid hormones, serological fluctuations of 17 β-estradiol and 11- ketotestosterone were found during gonadal maturation of M. australis. These hormones are the main hormones responsible for vitelogenesis and spermatogenesis processes, respectively. Conversely, 17,20 β-dihydroxy-4- pregnen-3-one did not show any serological fluctuation in females and males. Further studies involving gonadotropins, 17,20 β,21-trihydroxy-4-pregnen-3-one and vitellogenin quantification are required in order to obtain a more complete description of the reproductive physiology of wild and farmed M. australis.

Prevalencia de hipertensión arterial en la población infantil de una zona rural Prevalence of arterial hypertension in the child population in a rural area