No abstract

The fragmentation of primary alkoxyl radicals has been scarcely used in synthesis since other competing processes (such as oxidation or hydrogen abstraction) usually predominate. However, when serine derivatives were used as substrates, the scission took place in excellent yields. Tandem scission-allylation, -alkylation, or -arylation reactions were subsequently developed. This one-pot methodology was applied to the synthesis of unnatural amino acids, which are useful synthetic blocks or amino acid surrogates in peptidomimetics.

No abstract

A mild, one‐pot methodology to obtain α‐substituted nitrogen heterocycles from commercial amino acids is reported. This versatile procedure has been applied to the synthesis of different alkaloid analogues in good to excellent yields. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)

Intensive care units (ICUs) are stressful environments in which pain and human suffering are often experienced alongside great pressure and temporary urgency to perform work (van Mol et al., 2015). In these cases, health professionals are subject to extreme stress and work overload, and are often exposed during their work to occupational risk factors that have the potential to affect their mental health and psychological well-being over time (Gómez-Martínez et al., 2015). In fact, the literature has shown that, within ICUs, professionals may experience psychological problems such as burnout, stress, anxiety, and depression (Gómez-Martínez et al., 2015;van Mol et al., 2015). Nevertheless, many health professionals do not benefit from interventions introduced by psychology professionals in their organizations to improve their levels of mental health and psychological well-being, which could have serious consequences for workers, patients, and organizations (Bond et al., 2010;Waters et al., 2018).Psychosocial interventions to reduce stress and increase workers' well-being can take two main forms (Van der Klink et al., Clínica y Salud (2021) xx(x) xx-xx