The development of nanoscale biomaterials associated with polymers has been growing over the years, due to their important structural characteristics for applications in biological systems. The present study aimed to produce and test polymeric scaffolds composed of polylactic acid (PLA) fibers associated with a 58S bioglass doped with therapeutic ions for use in tissue engineering. Three 58S Bioglass was obtained by the sol-gel route, pure and doped with 5% strontium and cobalt ions. Solutions of 7% PLA was used as control and added the three different bioglass, 4% of 58S bioglass (PLA-BG), 4% bioglass-doped strontium (PLA-BGSr) and 4% bioglass-doped cobalt (PLA-BGCo). Scaffolds were produced through electrospinning process, and was characterized chemical and morphologically. The in vitro tests were performed using mesenchymal cells cultures from femurs of nine rats, grown in osteogenic supplemented total culture medium. After osteoblastic differentiation induction cell viability, alkaline phosphatase activity, total protein content quantification, and visualization of mineralization nodule tests were performed. Analysis of normal distribution used the Shapiro-Wilk test (nanofibers diameter and biological assay). Data were compared using the Kruskal-Wallis nonparametric test (p = 0.05). The bioglasses produced proved to be free of nitrate, chlorinated and nano-sized, with effective incorporation of therapeutic ions in their structure. All materials showed cell viability (>70%), total protein production, and alkaline phosphatase activity. It was possible to develop polylactic acid scaffolds associated with 58S bioglass doped with therapeutic ions without cytotoxicity. Scaffolds characteristics appear to sustain its application in bone tissue engineering.

<p><strong>Objective</strong>: The electrospinning is a widely adopted technique used to produce the polymeric fibers. The process depends on process parameters (voltage, flow rate and distance from capillary to the collector). The present study aimed to evaluate the influence of these parameters on chitosan fibers, a biopolymer used as scaffolds in dental and oral tissue engineering. <strong>Material and Methods:</strong> A solution of 7%(m/w) was prepared dissolving 0.7g of chitosan in 7 mL of trifluoroacetic acid (TFA) and 0.3mL of dichloromethane (DCM) (TFA/DCM - 70:30). After 12 hours, polymer solution (5 mL) was drawn into the syringe and pumped through needles of 0.4 mm internal diameter, at a rate of 0.8 mLh-1, different needle-tip-to-collector distances and voltages, for 10 min.  Electrospun fibers micrographies were obtained using the Scanning Electron Microscope for morphological analysis. <strong>Results</strong>: All voltages showed significant difference (p &lt; 0.0001) between them. At 15kV fibers showed higher concentration of beads. At 10 and 12 cm of distance there was no statistical significance (p &gt; 0.0001) but at 15 cm beads formation increased significantly (p &lt; 0.0001). At 12 cm fibers showed lowest fibers diameter in comparison to 10 and 15 cm (p &lt; 0.0001). There was no difference between 10 and 12 cm (p &gt; 0.0001) but in comparison to 15 cm both distances presented significantly difference (p &lt; 0.0001).  <strong>Conclusion</strong>: Thus, it can be concluded that morphology, in chitosan electrospun fibers, is influenced by the voltage and distance and this could describe the mohphological control of these structures.</p><p> </p><p><strong>Keywords</strong></p><p>Chitosan; Fibers; Electrochemical.</p>

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The objective was to synthesize and characterize fine polycaprolactone (PCL) fibers associated with a new 58S bioglass obtained by the precipitated sol-gel route, produced by the electrospinning process in order to incorporate therapeutic ions (Mg and Li). In PCL/acetone solutions were added 7% pure bioglass, bioglass doped with Mg(NO 3 ) 2 and Li 2 CO 3 and were subjected to electrospinning process. The fibers obtained were characterized morphologically, chemically and biologically. The results

Objective: To describe the clinical and histological aspects, as well as to discuss the diagnosis, treatment and preventive measures of actinic cheilitis (AC). Methodology: A literature review was carried out through the collection of articles indexed in the PubMed, Scielo and Regional Portal of the Virtual Health Library databases in the period 2002 to 2020, in addition to books on Oral Pathology and Stomatology. Results: It is important that, in dental practice, the professional is properly trained, especially the dental surgeon, as it is up to him the role of prevention, diagnosis, treatment and preservation of this clinical condition, with the necessary knowledge for this type of disease , because apparently simple lesions can potentially respond to progression to cancer. Conclusion: To prevent AC, the use of wide-brimmed hats and lip balm with sunscreen is recommended. The ideal treatment should be chosen according to the individual situation of each patient, and for acute AC prevention and conservative treatment is the best option, for chronic AC, total removal of the lesion is necessary.

Objetivo: O presente estudo teve como objetivo discorrer sobre a importância do cirurgião dentista em unidades de terapia intensiva para a manutenção da saúde bucal em pacientes sistemicamente comprometidos. Método: Foi realizada uma revisão de literatura com abordagem qualitativa. Foram selecionados artigos científicos indexados nas seguintes bases de dados online: Google Scholar e Pubmed. Os critérios de inclusão foram: artigos com disponibilidade na íntegra, escritos nos idiomas português e inglês, que apresentavam coerência com a temática e com data de publicação entre 2012 e 2020. Resultados: Pacientes internados em unidades de terapia intensiva apresentam comprometimento geral da saúde e, muitas vezes, devido às condições desfavoráveis da cavidade oral, podem desenvolver infecções pulmonares e ou generalizadas. A presença do Cirurgião-Dentista nas equipes interdisciplinares das UTIs colabora para a prevenção de infecções hospitalares, com diminuição do tempo de internação e do uso de medicamentos pelo paciente crítico, contribuindo de forma efetiva para o seu bem estar e dignidade. Conclusão: Os estudos relatam que, embora a presença do cirurgião dentista ainda não esteja consolidada em UTIs e a legislação brasileira apresente ainda lacunas para a inserção deste profissional em UTI, sua importância junto à equipe multiprofissional é indiscutível considerando a simplicidade e a efetividade das medidas que compõem os cuidados em saúde bucal.

Objetives: this study aimed to fabricate electrospun-based polyetherimide (PEI) fibers, under controlled parameters, and to perform a diameter analysis for potential mechanical improvement of dental materials. Material and Methods: PEI pallets (0.75 g) were dissolved in 2 mL of chloroform and then processed by electrospinning, under a flow rate of 1mLh1 , three different electrical voltages (10kV, 15kV and 20kV) and three distances (10 cm, 15 cm and 18 cm) between the needle tip and collector. These parameter combinations resulted in nine experimental groups that were analyzed using scanning electron microscopy (SEM) and image processing program for diameter measurement. Statistical analysis was performed using two-way ANOVA with post-hoc Tukey (5% significance). Results: from SEM images it was possible to observe formation of solid, misaligned and flawless defect-free fibers. And from the statistical analysis, distance (p = 0,0026) and the electric tension (p = 0,0012) showed a significant difference, but not for interaction between then (p = 0,4486). Conclusion: thus, it can be concluded that there is a possibility of the morphology control of PEI electrospun fibers, such as diameter, that can be used for a variety of applications such as incorporation in dental materials in order to improve its properties. Keywords Electrospinning technique; Fibers; Polyetherimide; Polymer.

Objective: To conduct a literature review on prefabricated fiberglass intra root pins. Methodology: A search was performed in the PubMed and Google Scholar databases with the following descriptors: “Post and Core Technique”, “Treatment” and “Dental Restoration Failure”. Results: Among the advantages of prefabricated intra root pins systems, one can highlight the low cost, simplicity of the technique, conservation of the remaining dental structure, elimination of the laboratory phase, and yet, the carbon fiber and glass pins have similar elasticity module that of dentin and similar flexion to that of the tooth, which reduces the risk of fractures when compared to molten metal cores. In addition, fiberglass pins have the advantage of being more translucent, which allows for a greater transmission of light, making them more aesthetic. Conclusion: Fiberglass pins are currently considered the best option for the rehabilitation of teeth treated endodontically with extensive coronary loss, since they have an elasticity module similar to that of dentin, flexion resistance, simplicity of the technique, less clinical time and have superior aesthetics to other intra root pins.