High resolution mass spectrometry can distinguish omicron sub-variants through the detection of peptide biomarkers associated with lineage-specific mutations within the surface spike protein.
Mass mapping using high resolution mass spectrometry can rapidly distinguish the omicron variant of the SARS-CoV2 coronavirus strains from other major variants of concern based on insertions, deletions and mutations within the surface spike protein.
Evolution of the SARS-CoV2 coronavirus charted using a mass spectrometry based protein phylogenetic approach for over 3000 spike S-proteins. The tree correctly resolves all major variants with single point mutations identified and displayed on the tree.
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