The performance of any enterprise is influenced by the environment in which it is located. The last two decades has witnessed the pre and post democratic governance in Nigeria as well as a number of government initiatives aimed at addressing some challenges facing the health delivery system of the country. The purpose of this paper was to study the capacity utilization of the pharmaceutical industry within the period to understand whether there was or no association in the performance with these changes. A survey of the capacity utilization in the production of solid and liquid dosage forms was carried out. A study of the availability and distribution of scientific workforce in the industry was also undertaken. Interviews were held with some individuals to gain more insight in the activities of the pharmaceutical industry. The scientific workforce within and among organizations varied considerably and the variation was influenced by perceived benefits and opportunities. The study showed that the capacity utilization of the pharmaceutical industry increased steadily but marginally over the period. There was reason to believe that the marginal increments were influence by the government policies and initiatives during this period, but could be better if some economic investments such as steady electricity were made. It was concluded that a sustained support and provision of infrastructures by the government together with trained and motivated scientific workforce are important in improving the capacity utilization in the pharmaceutical industry.
The purpose of this study was to investigate the influence of electrolyte type, pH, temperature and aging on the viscosity property of okra gum using paracetamol as model drug. Paracetamol (125 mg/ 5 mL) suspension containing okra gum particles of undersize 180 µm as suspending agent was formulated. Similar suspension of paracetamol was formulated using tragacanth gum as a suspending agent for comparison. Effect of electrolyte type, pH, temperature and aging on the viscosity property of okra gum in paracetamol suspension was evaluated using standard methods. Addition of electrolytes, changes in pH, increase in temperature and increase in storage time were shown to decrease the viscosity of the paracetamol suspension. The effect of temperature and aging on the viscosity of the suspension formulation containing okra gum was more pronounced than on the formulation containing tragacanth gum. Conversely, the effect of alkaline pH and type of electrolyte on the viscosity of the suspension formulation containing tragacanth gum was more pronounced than on the formulation containing okra gum. On the basis of these, formulators and caregivers may consider these factors when designing or using pharmaceutical suspensions containing natural gums such as okra and tragacanth as viscosity enhancing agents.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.