Contact lenses are a safe and effective mode of vision correction used by more than 100 million people worldwide, yet some adverse responses to microbial contamination of contact lenses still occur. Various medical devices, including contact lens cases, currently use antimicrobial agents to eliminate or reduce microbial contamination at the surface. The application of antimicrobial surface technologies to contact lenses and lens cases is being explored. This article describes agents that hold promise for antimicrobial surfaces for contact lenses or lens cases.
The accuracy of the gradient technique for measuring the clinical accommodative convergence to accommodation (AC/A) ratio is dependent upon obtaining veridical heterophoria measurements. However, previous studies have demonstrated that the sustained output of slow fusional vergence, which may take several minutes or even hours to decay, can bias heterophoria assessment. In the clinical setting, it is usual to estimate the AC/A ratio after just a few seconds of dissociation. This study investigated whether the slow fusional vergence response alters this crosslink ratio by comparing values of AC/A measured both before and immediately after a 1-hr period of continuous monocular occlusion. Sustained occlusion produced a significant change in near heterophoria in 10 out of the 21 subjects examined, but no significant change in AC/A was observed in either the adapting or non-adapting subgroups. Accordingly, while the sustained output of slow fusional vergence will influence clinical measurements of heterophoria, its presence does not alter the stimulus AC/A ratio significantly.
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