Increasing autonomy and sustainability are major goals in manufacturing. Main technological trends provide enablers for achieving these goals and need to be implemented and combined in manufacturing machinery in a suitable manner. The paper exposes a vision of modern manufacturing machines, where the complexity of manufacturing processes is handled within the manufacturing machine and a simplistic front end is presented to the operator, which means that major elements of operators' tasks are fulfilled by the intelligence of the machine. Research vectors paving the ground for this concept from different points of view are then discussed. Research is presented on intelligent grinding, intelligent recognition and suppression of chatter, adaptive thermal and motion error compensation exploting also self-learning abilities. It is necessary to point out, that not only intelligent mastering of process and machine becomes more and more important but communications among machine tools enabling process chain overarching intelligent approaches and creating intelligent factories.
Schon im Jahre 1867 stellte GStte (1) bet Hfihnchenembryonen durch makroskopische Priiparation festl), dass das Pankreas aus drei An]agen entsteht, einer dorsalen und zwei sparer hinzukommenden ,,sekundaren" (ventralen) Anlagen. Derselbe Forscher (2) hat sodann, neun Jahre spi~ter, auch ffir einen Anuren (Bombinator igneus) eine dreifache An]age des Pankreas gefunden. Von zwei ventralen, aus dem primitiven Leberstiel hervorsprossenden blindsackfOrmigen Ausbuehtungen verbindet sieh die rechte, indem sie yon dem Leberstiel nach links hil~iiberwachst, mit der linksseitigen und verliert ihre eigene Mfindung in den Darm. Indem sie ferner auf der rechten Seite des Darmes dem herabwuchernden dorsalen Pankreas entgegenwaehst, vereinigt sie sich auch mit diesem. Das dorsale Pankreas verliert darauf bet Bombinator seine eigene Mfindung und es er-5ffnet sich die gesamte Organanlage somit sehliesslich Imr an einer einzigen Stelle, entsprechend der linken ventralen Ausstfilpung, in den Darm.Diese Angaben G(ittes blieben tange Zeit unbeachtet, bis sie erst im Jahre 1881 dureh GOppert (ll) der Vergessenheit entrissen wurden. Nachdem schon Oppel (7) bet Proteus fest-1) Nach Felix (16.) citiert, da die Arbeit mir nicht zugiingig war.Anatomisehe Hofto. I. Abteilung XX1V. Heft (8. Bd, tL 1).(J ~l Einleltung.
ANSWERClinical Course. Based on the histological findings, the tumor was classified as an adenomyoepithelial tumor and the patient was referred to Mohs surgery for complete resection with nail plate excision to ensure negative margins and prevent recurrence. Excision of the remaining lesion with a 2 mm margin of normal tissue was completed down to the level of the periosteum. A review of horizontal frozen sections intraoperatively showed no residual tumor at the margins examined, and the surgical defect was closed in a linear fashion along the periungual fold (Fig. 3A). At follow-up, there was no regrowth of the tumor at 7 months postoperatively (Fig. 3B). FIGURE 3. A, B, Closure immediately after excision (A) and good healing without recurrence 7 months postoperatively (B).
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