Nicholas reactions on the cation derived from the cyclic allylic acetate alkynedicobalt complex 1 favour the γ-site kinetically for most nucleophiles, with increasing amounts of αproducts in cases with greater nucleophilicity. Some regiocontrol in introduction of a specific nucleophilic fragment is possible by using different nucleophiles. Under conditions where reversibility is possible, the thermodynamically favoured site is exclusively γ- .

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