Publishing is part and parcel of a successful academic career, and Covid-19 has amplified gender disparities in manuscript submissions and authorships. We used longitudinal publication data on 431,207 scientists in biology, chemistry, and clinical and basic medicine to quantify the differential impact of Covid-19 on women's and men's annual publishing rates. In a difference-in-differences analysis, we estimated that the average gender difference in publication productivity increased from -0.26 in 2019 (corresponding to a 17% lower output for women than men) to -0.35 in 2020 (corresponding to a 24% lower output for women than men). An age-group comparison showed a widening gender gap for both early career and mid-career scientists. The increasing gender gap was most pronounced among highly productive authors and scientists in clinical medicine and biology. Our study demonstrates the importance of reinforcing institutional commitments to diversity through policies that support the inclusion and retention of women researchers.

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