Therapeutic endoscopic ultrasound (EUS) became possible after the advent of the linear echoendoscope and the EUS guided fine needle aspiration. Over the past two decades, the indications for therapeutic EUS have expanded and evidence regarding its utility has been steadily accumulating. Randomized studies have shown EUS to be effective for cancer pain relief (celiac plexus neurolysis), pancreatic fluid collection drainage, and biliary drainage. Prospective studies have shown EUS-guided biliary drainage to be safe and effective in patients with failed ERCP. There is evidence to suggest that EUS is effective for pancreatic duct drainage, gallbladder drainage, and drainage of pelvic collections. EUS may also be useful for targeted cancer treatment via brachytherapy, radiofrequency ablation, or injection therapy. Therapeutic EUS is likely to play an increasingly important role in endoscopic therapy of gastrointestinal diseases in the near future.
Results 60 patients underwent colonoscopy for colonic tumors. The average age was 55.60 years old, 53.3% were females, 85% had a family history of colon cancer and 50% were smokers. A significant association of Pap stain in detecting malignancy (p=0.002) was noted with a sensitivity of 79.2% and specificity of 66.6%. Conclusions The results show good sensitivity of using Pap stain in that it is able to correctly identify 79.2% for patients who truly have colonic tumors with specificity of 66.6%. There is a significant association between Pap stain and H&E stain in detecting malignancy (p=0.002) in that a positive Pap stain is highly associated with colon cancer detection (PPV=90.5%) and only 44.4% will be truly negative for those who have no colon cancer.
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