Crystallization from solutions was applied to produce stoichiometric and crystalline hydroxyapatite (HAP) suitable for use as a biomaterial. This was accomplished by keeping a low supersaturation through the following procedure: semi-continuous operating mode, slow reactant addition rate and addition of a calcium complexing agent. A high temperature (90 °C) and probably carbonate incorporation also favored the formation of a well crystallized material. A qualitative correlation was found between the supersaturation and HAP properties such as crystallinity and particle size
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