Studies of the tissues of the human olfactory mucosa have been performed to investigate olfactory dysfunction and, more recently, olfactory mucosa has attracted a novel interest of investigators because it can be used as an early marker of neurodegenerative conditions of the brain and as a source of multipotent neural stem cells, with applications in regenerative medicine. The olfactory mucosa is readily available to the otolaryngologist, but the harvesting of this tissue must be safe, effective, and reliable, obtaining as little tissue as necessary, while avoiding unnecessary harm to the remaining olfactory tissue and function. The purpose of this review is to summarize the results of the most important studies and knowledge with regard to the human olfactory mucosa and its applications, emphasizing the issue of the distribution of the olfactory mucosa in the nasal cavities.
POSTERSand safe modality for early glottic carcinoma, although current probe size is not enough small. This should be regarded as a pilot study. Laryngology/Broncho-Esophagology Treatment of Epiglottic Cyst by Radiofrequency SnareAnnie Zhou (presenter) Objective: Epiglottic cysts are common in clinic and are excised by operation. Our department adopts domestic radiofrequency therapy apparatus which is low in cost. At the same time, the radiofrequency ablation of the radiofrequency treatment group has the function of stopping bleeding and reducing recurrence.Method: All 40 patients were divided into 2 groups according to random numerical expressions. The epiglottic cyst of the 20 patients in the treatment group was excised by radiofrequency snare and that of patients in the control group was excised by routine operation. Results:The postoperative pathological diagnosis of the 40 patients was in accordance with epiglottic cyst. The curative rate in radiofrequency treatment group is 100% and in routine operation group is 95%.Conclusion: With our operation, the thrombus formation and the vascular occlusion have good anastalsis. The snare can be freely operated under the under self-retaining laryngoscope to ablate masses, which maximally protects the surrounding normal tissues. Laryngology/Broncho-Esophagology Ultrasonic Aspirator-Assisted Laryngeal Framework SurgeryJames Daniero (presenter); Joseph Spiegel, Maurits Boon, MD Objective: (1) Demonstrate the utility of the ultrasonic surgical aspirator in minimizing the risk and simplifying laryngeal framework surgery. (2) Determine the benefits using of this technique in the setting of resident education.Method: Case series using the SONOPET ultrasonic surgical aspirator (MIWATEC Co., Ltd.) to enable precise dissection of laryngeal cartilage without thermal or mechanical injury to the surrounding soft tissue or mucosa. We describe the first application of this technology in the in vivo larynx for type I thyroplasty and laryngofissure approaches.Results: Laryngeal framework surgery using current techniques have the limitations of difficulty incising calcified cartilage, mechanical chatter, thermal injury, and soft tissue damage. The ultrasonic surgical aspirator was used in four medialization thyroplasty procedures and two laryngofissure approaches for open laryngoplasty without intraoperative or postoperative complications. No infections or inadvertent soft tissue damage were observed. There were no complications of implant placement or with early healing. Finally, a very slight learning curve exists for its use in resident performed procedures and time to perform cutting tasks was faster than standard techniques.Conclusion: The ultrasonic surgical system may be used as an alternative to standard surgical technique, surgical drill, or oscillating saw for laryngeal framework surgery. Limited learning curve exists and our results indicate that the device can be used safely and in a reasonable amount of time.Objective: 1) Evaluate the validity of the translated and cult...
OBJECTIVE:To retrospectively review the efficacy and safety of endoscopic sinus surgery (ESS) without postoperative nasal packing for the treatment of chronic rhinosinusitis (CRS). METHOD: Charts were reviewed from 154 patients with CRS who underwent ESS without postoperative nasal packing or the use of hemostatic agents at the conclusion of surgery. Operative blood loss, postoperative sinonasal pain assessed via a visual analog scales (VAS) from 0-10, surgical outcome, and the incidence of postoperative complications such as bleeding were reviewed. RESULTS: Seventy-one women and 83 men with a mean age of 45.5 years were included in the study. Mean estimated operative blood loss was 128.3 mL (range: 10-650). Epiphora and eye discomfort/pressure were present in 14 (9.1%) and 10 (6.5%) patients, respectively. Mean VAS for sinonasal pain was 0.98. Two subjects (1.3%) experienced primary postoperative bleeding requiring nasal packing with petroleum gauze for 1 and 3 days, respectively. No delayed nasal bleeding or other serious complications occurred. The recurrence rate of CRS was 5.8% (9/154). Two patients underwent revised ESS. CONCLUSION: ESS without postoperative nasal packing is feasible and safe. Efficacy of Herbal Treatment for Olfactory DysfunctionKojiro Hirano, MD (presenter); Yasuyuki Hinohira, MD, PhD; Jun Uchida, MD, PhD; Harumi Suzaki, MD, PhD OBJECTIVE: 1) Evaluate the efficacy of Chinese herbal medicine for patients with severe olfactory dysfunction using T & T olfactometer. 2) Establish the indication of the novel therapy. METHOD: 121 patients diagnosed as severe olfactory dysfunction caused by the olfactory epithelial disorders were subjected to this study. All of them were refractory for prior medical treatments including a topical nasal drop of adrenocortical hormone. They consisted of 35 males and 86 females, and the ages of the patients ranged 26 to 83. They were randomly divided into two groups according to kinds of Chinese herbal medicines such as 'ninnjinnyoueitou (N)' or 'toukishakuyakusann (T).' The two groups were treated by internal use of the medicines for 3 to 6 month, respectively. They were evaluated as Fine, Improvement, or Unchanged after the treatment, using T & T olfactometer. RESULTS: 28% of the N group showed Fine and 6% Improvement although 65% of them showed Unchanged. The T group showed that Fine is 3% and Improvement 38%. 30 to 40% of the patients subjected to this study showed at least improvement in their olfactory function. There was no significant difference between both groups. No patients encountered any complications. CONCLUSION: It has been reported that only a topical steroid nasal drop is effective for the patients diagnosed as severe olfactory dysfunction caused by the olfactory epithelial disorders. Our study indicated that Chinese herbal treatments have certain efficacy for the patients, who were refractory for prior medical treatments including a topical steroid nasal drop. Efficacy of Intrathecal Fluorescein in CSF LeakRepair Pete Batra, MD (presenter); Karth...
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