The genus Croton, belonging to the Euphorbiaceae family, is a plant with shrubby characteristics, with the ability to regrow in times of rain, develops wildly, especially in deforestation areas, being reported mainly in the Caatinga and Forest region. One of the main characteristics of this genus is that several species are rich in chemical constituents of importance for medicine. In this way, this review of the literature, has an objective that findings regarding the biological activities and chemical composition of Croton species. This study is a literature review, carried out in the following databases: SciELO, BVS, MEDLINE, LILACS, PubMed and ScienceDirect, with a time frame between 1997 and 2020. The articles studied have shown different activities for Croton species, such as anti-inflammatory, antihypertensive, antifungal, antimicrobial, antidiabetic, antioxidant, antinociceptive and anti-tumor. Regarding toxicological aspects, the findings suggest caution in the use of Croton species, as some are toxic. While, regarding the chemical composition, in most species the presence of several secondary metabolites is observed, such as alkaloids, terpenoids, flavonoids and other phenolic compounds. Therefore, the results described in this article suggest that the therapeutic application of Croton species is supported by the literature, however we point out that caution is required in the use of Croton species, some present due to toxicity.
Aspectos botânicos e propriedades farmacológicas de calendula officinalis: uma revisão Botanical aspects and pharmacological properties of calendula officinalis: a review
Introduction: Mental disorders are more and more frequent. In Brazil, primary care makes possible the population's first encounter with mental care, having medicines as one of the main therapeutic applied resources, which are made available in different ways, including the municipal primary pharmacy. Psychotropic drugs, such as anxiolytics, act on these mental disorders, improving the quality of life and providing freedom to the individual, however, their use irrationally and for a prolonged period of time causes harm to those who use them. Objective: To know the aspects surrounding the consumption of anxiolytic drugs, as well as to identify individual and collective characteristics of the participants that lead to their use. Methodology: Cross-sectional descriptive research with a quali-quantitative approach, carried out with prescriptions that contained anxiolytics and questionnaires answered by patients treated at the basic pharmacy in the city of Flores - PE. Results: The female gender, age group over 41 years, low education, presence of children and marriage were related to the increase in the use of anxiolytics, in addition, the emergence of effects caused by treatment abandonment, interactions regarding the use of plants or more of a drug with anxiolytics and the errors of gifts in prescriptions had high rates. Conclusion: The delineation of the profile of individuals who use anxiolytics as therapy provides the creation of policies at specific groups in order to reduce the therapy with them, in addition, knowledge of the main errors in prescriptions and the presence of interactions ensures a better treatment success.
Propriedades terapêuticas do gênero cleome, familia cleomaceaeTherapeutic properties of the cleome gender, cleomaceae family
Introduction: Over time, treatments with plant species have become more effective for the vast majority of the population, even with a vague collection of scientific research that proves their safety and effectiveness. Among these different species is the arboreal Crescentia cujete L., which is widely distributed in Northeastern Brazil. It is applied with various therapeutic purposes, from antihypertensive, analgesic, antispasmodic and some gynecological disorders. Objective: To analyze the possible cytotoxicity of the hydroalcoholic extract of the fruit. Methodology: The extract was obtained through dynamic maceration in a hydroalcoholic solution. A cytotoxicity analysis was carried out based on the methodologies of osmotic fragility and lethality against Artemia salina L. 45.32%. Conclusion: Therefore, further research aimed at safety and possible applicability of the extract in question is encouraged.
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