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The treatment of venous vascular malformations with Photo-Derm® is safe and effective as it offered a high degree of patient satisfaction and good results in the disappearance of the lesions.

The following study reports the development of modified electrode with reduced graphene oxide (ErGO) for the voltammetric determination of 17α‐ethinylestradiol (EE2). The structural and morphological characterizations of the rGO were carried out by FTIR, Raman, UV‐Vis, TEM and SEM, and showed the typical formation of the nanomaterial. Electrochemical analyses were performed using Differential Pulse Voltammetry (DPV). Under optimized conditions, an analytical curve was generated for the sensor, which presented a linear dynamic range (LDR) from 0.04 to 8.28 μmol L−1 (R2=0.9999), with limit of detection (LOD) of 6.79 nmol L−1 and limit of quantification (LOQ) of 22.60 nmol L−1. The reproducibility and repeatability studies showed relative standard deviations (RSD) of 2.31 % and 5.23 %, respectively. ErGO was used to determine EE2 in wastewater, tablets, and synthetic urine samples with recovery values between 94.8 % and 110.1 %. The results obtained with ErGO show that the developed sensor can be used for the identification and quantification of EE2 in several matrices, due the excellent analytical performance presented.

Estrone (E1) is associated with various health and environmental issues, necessitating the development of analytical methods for monitoring E1 in different matrices. In this context, the present study reports the development of a graphene quantum dot‐based electrode (GQD/E) to detect estrone in water and urine samples. Voltammetric measurements under optimized conditions demonstrated the feasibility of using GQD/E to detect estrone at trace levels in aqueous samples. Two linear dynamic ranges were obtained at concentrations from 0.05 to 10.00 μmol L−1, with limit of detection (LOD) and quantification (LOQ) of 28.0 and 96.0 nmol L−1, respectively. Furthermore, the LOD value obtained in this study is one of the lowest ever reported in the literature for the electrochemical determination of E1. The method response showed no significant variation in the current intensity of E1 in the presence of the 16 interferents. The recovery values obtained by using GQD/E to quantify estrone in fortified samples of seawater, tap water, wastewater and synthetic urine ranged from 95.9 to 108.1 %, indicating that the method presents highly sensitive for detecting estrone in aqueous matrices.

The induction of polyploidy in Eucalyptus can lead to higher-yielding and more adapted clones, with better wood quality. After artificial polyploidization, it is necessary to certify the effectiveness of the process through cytogenetic analyses and anatomical trait evaluations. Thus, the aim of this study was to certify the chromosome duplication in artificially polyploidized clones of Eucalyptus grandis × Eucalyptus urophylla using cytogenetic analysis, flow cytometry, and leaf anatomy measurements. Chromosomal counts and DNA content estimation allowed the identification of artificially polyploidized clones and mixoploids. Polyploid clones had larger stomata diameter than diploids. The increase in stomata size was accompanied by lower stomatal density in most polyploid clones. The typical gigas effect of polyploidized plants was demonstrated by the expressive increase in leaf area in polyploid individuals compared to diploids. Our findings indicate that the use of polyploidy in Eucalyptus breeding is promising, allowing the discrimination of diploid, tetraploid, and mixoploid plants.

Nesse artigo, apresentamos vários paradoxos aparentes da relatividade restrita e suas respectivas soluções. Esse paradoxos aparecem desde o advento da relatividade, em 1905, e de fato nunca são paradoxos. Do ponto de vista didático, os paradoxos são uma excelente ferramenta de aprendizado. Eles levam o estudante a confrontar, e abandonar, vários conceitos centrais da teoria Galileana, como a simultaneidade e a rigidez dos corpos extensos. Particularmente, revisaremos uma nova e simples solução para o paradoxo dos gêmeos, encontrada recentemente por um dos presentes autores [1]. Ela não necessita considerar referenciais acelerados ou sinais de luz, que são as soluções apresentadas na literatura.

Patients with systemic lupus erythematosus have a poor prognosis of pregnancy, since it is associated with significant maternal and fetal morbidity, including spontaneous miscarriage, pre-eclampsia, intrauterine growth restriction, fetal death and pre-term delivery. We report a case with successful pregnancy in a patient with systemic lupus erythematosus and hypertension.A 39-year-old nulliparous woman presented with systemic lupus erythematosus with antinuclear and antiphospholipid antibodies, hypertension and recurrent pregnancy loss presented for assisted reproduction. The patient responded well to enoxaparin and prednisone during both assisted reproduction and prenatal treatment.This case report indicates that prescription of immunosuppressant and blood thinners can be safely recommended throughout the whole prenatal period in patients with systemic lupus erythematosus. Enoxaparin and prednisone may be prescribed concurrently during pregnancy.

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