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The use of Mikania glomerata Spreng. (Guaco) in the treatment of respiratory allergy -an integrative review O uso de Mikania glomerata Spreng. (Guaco) no tratamento de alergia respiratória -uma revisão integrativa SOUSA, Kyanne Adrielle Gadelha (1) ; NASCIMENTO, Arthur Noronha Costa do (2) ; PEREIRA, José Carlos da Silveira (3) ; NUNES, Luanne Eugênia (4) ; ARAÚJO, Ítalo Diego Rebouças de (5)

In this study, we evaluated the ovicidal and larvicidal activity of protein preparations obtained from Cassia fistula L. and Combretum leprosum Mart. leaves on the gastrointestinal parasites of goats. Protein preparations were obtained after the extraction of C. fistula L. and C. leprosum Mart. leaves, followed by protein fractionation (with ammonium sulfate saturation percentages of 30%, 30%-60%, and 60%-90%) and dialysis, which resulted in protein fractions (called F1, F2, and F3, respectively). The fractions were evaluated by egg hatching (the eggs were recovered in stool samples from naturally infected goats) and larval development tests. The results reveled that the inhibition of hatching of eggs caused by the protein fractions of C. fistula (38%) were similar to that of the control drug, thiabendazole. In addition, the fractions of C. fistula caused significant inhibition (61-69%) of larval development also. However, C. leprosum did not reveal significant inhibition of egg hatching and larval development. We conclude that C. fistula L. showed better ovicidal and larvicidal activity against endoparasites.

The quality of meat produced with low sodium chloride and prepared with lactic acid and sodium lactate was evaluated. Meat samples were divided into the following groups according to the treatment: 1% lactic acid (MLA), 3% sodium lactate, a combination of both (MLA + SL) and without preservatives (MC). Samples were salted with 2% sodium chloride and then stored under refrigeration at 4 ± 1 °C for 12 days. Microbiological changes (coliforms at 35 and 45 ºC, Salmonella sp., Staphylococcus spp., mesophilic, and psychotrophic aerobic bacteria) and physicochemical alterations (pH, color, WHC, CL, SF, and TBARS) were analyzed at three, six, and twelve. The meat treated with natural preservatives presented lower microbial counts when compared to the MC group. Excellent MLA, with a longer shelf life of up to 6 days in refrigerated storage. Regarding the physical–chemical parameters, it was verified that the introduction of preservatives did not significantly alter the quality of the product. Thus, natural preservatives may be viable alternatives for the production of meat with longer storage time and low NaCl content. Practical applications In this work, we report the addition of natural preservatives, lactic acid and sodium lactate to promote an increase in the shelf life of up to 6 days of beef and low sodium chloride. This is important because it allows the consumer to guarantee quality and safety in the consumption of the food for a longer period, thus reducing the possibility of developing diseases caused by the excessive consumption of NaCl. For the industry, the introduction of organic acids in beef, in addition to reducing the NaCl content, which makes the product more attractive to the consumer seeking a healthier diet, makes it possible to commercialize it without altering the sensorial characteristics.

This study characterizes the allelopathic effect in the germination of Allium cepa seeds, and toxic on the species Artemia salina, of aqueous extracts of leaves of Aspidosperma pyrifolium and Combretum leprosum and the constituent phytochemical compositions. For this, Allium cepa seeds were germinated in systems containing aqueous extracts (200, 400 and 800 mg.L-1) and distilled water, to evaluate aspects of germination, mitotic phases, mitotic index and limit value of cytotoxicity. The toxicity of the aqueous extracts was evaluated in Artemia salina. The extracts were evaluated qualitatively and quantitatively when the substances present to define the phytochemical profile. The aqueous extract of A. pyrifolium negatively affects the germination process in the hypocotyl and seedling growth at 800 mg.L-1. The LC50 found for the aqueous extract of A. pyrifolium was 4986 mg.L-1. The effect of C. leprosum extract on germination resulted in an increase in the dry matter of the root at 400 mg.L-1 and in the density of the dry matter of the root at 800 mg.L-1. In addition, it reduces the seedling matter at 200 mg.L-1, corresponding to the trend observed in the mitotic index, in which this concentration presented a sublethal score for the limit value of cytotoxicity. The maximum concentration evaluated was not sufficient to determine an LC50 in A. salina. The phytochemical profiles of both species demonstrated classes of substances with potential pharmacological application. This information is important because these species are commonly used as food for farm animals and for purposes in folk medicine.

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