, with radiochemical purity > 98% and mean specific radioactivity at the end of synthesis 3.7 ± 0.9 GBq/µmol. With this method the amounts of the reagents used in the synthesis are considerably reduced in comparison to other electrophilic labeling approaches. Thus the manipulations during the synthesis and the purification of the product are simplified.
The caries experience and dental fluorosis of 84 Danish children, who had used fluoride tablets for 1-4 yr in the period 1976-80, were compared with those of a group matching in sex, age, place of living, and socioeconomic status. The average age of the children at the time of examination was 5.8 yr. A recording of mothers' attitudes to dental care, knowledge about tooth brushing, attitudes to candy, and number of teeth in the maxilla showed no difference between the fluoride tablet group and the non-users' group. Moreover, there was no significant difference between the two groups with respect to dental caries. The findings are discussed in relation to recent reports on the decline of dental caries resulting from widespread use of local administration of fluorides.
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