The aim of this study was to estimate the seroprevalence rates of human immunodeficiency virus (HIV), hepatitis B virus (HBV, core antibody), hepatitis C virus (HCV), and syphilis infections and analyze associated risk factors among 504 non-injecting cocaine users (NICU) in Buenos Aires, Argentina. Participants were interviewed in face-to-face sessions through a short structured questionnaire. Using venipuncture, 10mL of blood was collected. Seroprevalence rates were: HIV (6.3%), HBV (9%), HCV (7.5%), and VDRL (4.2%). The risk of being infected with HIV, HBV, and HCV was significantly associated with having had a sex partner who was either a drug injector or who was known to be HIV positive. HIV and HCV infections were associated with former imprisonment, and HCV was associated with having been tattooed. Because of the rising number of NICU and the multiple infections detected, it is essential to implement prevention strategies focused on this population.
Objective To describe the prevalence and correlates of low serum Se and determine whether HIV, hepatitis C virus (HCV) and/or types of drugs used are associated with serum Se in a cohort of infected and uninfected drug users. Design Independent correlates of low serum Se levels based on data collected from food recalls, physical exams, and clinical status questionnaires were identified using multivariate analysis. Setting Buenos Aires, Argentina Subjects A total of 205 (25 females and 180 males) former and current drug users Results Drug users had an average serum Se level of 69.8±32.8 μg/dl, and 82% were considered deficient (< 85μg/l). Multivariate analyses found that HIV and/or HCV infection had lower mean Se compared to healthy, uninfected drug users (HIV/HCV co-infection: −25.3 μg/l (SE =7.6, p=0.001); HIV alone: −28.9 μg/l (SE=6.9, p<0.001); HCV alone −19.4 μg/l (SE = 7.1, p=0.006). Current and previous drug use was associated with higher serum Se. Cigarette smoking and heavy alcohol consumption were not found to be associated with Se status. Conclusions Low serum Se levels are highly prevalent among drug users in Buenos Aires, Argentina. Se supplementation and/or dietary interventions may be warranted in drug users who are at high risk of HIV and/or HCV infection.
In the results paragraph of the Abstract, instead of: Drug users had an average serum Se level of 69?8 (SD 32?8) mg/dl, and 82 % were considered deficient (,85 mg/dl).it should read: Drug users had an average serum Se level of 69?8 (SD 32?8) mg/l, and 82 % were considered deficient (,85 mg/l).Serum Se units of mg/l are correct as published in the remainder of the research article. ReferenceSheehan HB, Benetucci J, Muzzio E, Redini L, Naveira J, Segura M, Weissenbacher M & Tang AM (2011) High rates of serum selenium deficiency among HIV-and HCV-infected and uninfected drug users in
e J. R odrigues d a S ilva **S: t Como contribuição in icia l para o estudo das a n em ias n a s in fâ n cia , ap resen tam os o p resente trabalho, p arte de um program a de a v aliação das con d ições sa n itárias da in fân cia n a G u anab ara. Os A A . r e la ta m os a ch a d o s h em a to ló g ico s e m 100 cria n ça s, 96 ã a s q u a is se a p r e s e n ta v a m co m a n e m ia de diversos graus, se n d o 79% ferro p ên ica s, 2% m ac ro cítica s e 15% n o rm o crô m ica s, a m a io ria ã as quais a sso cm ã a s à h ip o p ro te in em ia , h a v e n d o c o n c o m itâ n c ia n o a u m e n to daOs ach ad os h em atológicos do san gue p e riférico de um g ru p o de 100 cria n ça s ab ri gadas n a F undação R om ão M attos D uarte, organização filan tróp ica d e s tin a d a à in te r nação de m enores aband onad os no Estado da G uanabara são apresentados a seguir, com os com entários das várias etap as que foram a n alisad as. MATERIAL No segundo grupo (quadros II-A e II-B ), estão as crian ças m aiores de 6 anos, num to ta l de 45 d oen tes. In icialm en te, apresen tam os a série verm elh a e, separadam en te (quadros III-A, III-B , IV-A e IV -B) os de m ais ach ad os h em a to ló g ico s nos p acientes. P ara a va lia çã o h em a to ló g ica RESULTADOS:No gru p o d e 1 a 6 an o s, encontram os 42 casos de an em ia hipocrôm ica (76,3% ), 10 casos de an em ia norm ocrôm ica (18,1%) e 2 casos de an em ia m acrocítica (3,6% ), com * T ra b a lh o d a C ad eira de C línica de D oenças T ro p ic a is e In fec tu o sas d a F a c u ld a d e de M edicina da U n iv e rsid a d e F e d e ra l do R io de Ja n e iro ** A ssisten tes P ro fe s so r C ated rático
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