Non-melanoma skin cancers (NMSCs) are the most common type of human cancer, with basal cell carcinomas representing the majority of these cancers. The following article will focus on a review of the current knowledge regarding incidence, risk factors, and pathogenesis, including genetics, clinical features, and treatment options of basal cell carcinomas.

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Systemic treatment leads to objective responses in locally advanced cutaneous SCC that are not amenable to local cure.