We have designed a novel QSM algorithm that addresses some of the limitations of existing techniques that combine the background removal and dipole inversion steps in a single step. We propose that the solution to the direct inversion problem can be aided by an iterative k-space algorithm and the inclusion of a priori information that represents feature-based and voxel-fidelity-based constraints. The considered approach, when compared with other techniques, resulted in a more accurate depiction of the susceptibility in high susceptibility deep gray matter (dGM) structures without sacrificing performance in regions like the cortex of the brain.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.