BackgroundTelehealth solutions can improve the safety of ambulatory chemotherapy, contributing to the maintenance of patients at their home, hence improving their well-being, all the while reducing health care costs. There is, however, need for a practicable multilevel monitoring solution, encompassing relevant outputs involved in the pathophysiology of chemotherapy-induced toxicity. Domomedicine embraces the delivery of complex care and medical procedures at the patient’s home based on modern technologies, and thus it offers an integrated approach for increasing the safety of cancer patients on chemotherapy.ObjectiveThe objective was to evaluate patient compliance and clinical relevance of a novel integrated multiparametric telemonitoring domomedicine platform in cancer patients receiving multidrug chemotherapy at home.MethodsSelf-measured body weight, self-rated symptoms using the 19-item MD Anderson Symptom Inventory (MDASI), and circadian rest-activity rhythm recording with a wrist accelerometer (actigraph) were transmitted daily by patients to a server via the Internet, using a dedicated platform installed at home. Daily body weight changes, individual MDASI scores, and relative percentage of activity in-bed versus out-of-bed (I

This paper presents a novel health monitoring system for Parkinson's disease (pd) patients called help (Home-based Empowered Living for Parkinson's disease patients). The help system has been specifically designed and implemented as a health monitoring system in order to optimize treatment and improve quality of life of people with Parkinson's. This is a challenging goal due to the difficulty in establishing a closed-loop system that is able to detect the outcomes of treatment and react accordingly. In a similar way to diabetes treatment where the plasma glucose level can be measured and can be used to regulate drug doses, the help system's approach aims to estimate pd symptoms and to adjust the dose of medication in order to reduce symptoms. The proposed health monitoring system is composed of several components: a body sensor & actuator network managed by a smartphone, a remote monitoring platform for doctors and clinical professionals as well as a telecommunication and service infrastructure. The real advantage derives from having constant medical control without dramatically modifying daily life. The help system is going to be evaluated in several cities during the first part of 2012 under daily living conditions with pd patients.Keywords: Parkinson's Disease, Body Sensor and Actuator Network, Health Monitoring System, Ambient Assisted Living ResumenEn este trabajo se presenta un nuevo sistema de vigilancia de la salud para pacientes con la enfermedad de Parkinson (ep), pacientes llamados help (Fortaleciendo la vida en el hogar de pacientes con la enfermedad Parkinson). El sistema de ayuda ha sido específicamente diseñado e implementado como un sistema de vigilancia de la salud con el fin de optimizar el tratamiento y mejorar la calidad de vida de las personas con Parkinson. Este es un objetivo difícil debido a la dificultad del establecimiento de un sistema de circuito cerrado que es capaz de detectar los resultados del tratamiento y reaccionar en consecuencia. Es una manera similar al tratamiento de la diabetes donde el nivel de glucosa en plasma se puede medir y se puede utilizar para regular las dosis de medicamentos; el enfoque del sistema

Crumbs and places, is a platform that aims to build a virtual image of the world based on geo-localized human activity. Relationships between people occur in places that are determinant in the kind of links that are established between people of the same community.

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TPS9154 Background: Self-rated symptoms contribute to the Quality of Life (QoL) of cancer patients (pts) and impact on prognosis. Behavioural functions are controlled by the circadian timing system (CTS), through a network of molecular clocks that time cellular proliferation and drug metabolism (Lévi et al. ARPT 2010). Chronotherapy aims at the reduction of treatment-related symptoms through the adjustment of chemotherapy delivery to the CTS. Cancer chronotherapy is delivered at home using programmable pumps, and avoids familial and social disruption. Telemedicine tools can provide continuous information on symptoms, behavior, QoL and CTS from non hospitalized pts. Methods: The inCASA platform enables telemonitoring of multiple functions in order to help physicians to detect early warning signals in pt condition at home, and prompt adequate and timely interventions. Our pilot site investigates the clinical relevance of daily teletransmitted self assessed symptoms, body weight and rest-activity circadian rhythm in cancer pts. This system was first well understood and accepted by 14 pts (9 male, 5 female, 43-77 years) at the outpt clinic, then used by 5 pts (4 male, 1 female, 61±13 years) at home daily for 6+ weeks, while receiving chronotherapy. The pilot phase will accrue 30 pts receiving chronotherapy at home from 03/01/2012. Pts will fill in the M.D. Anderson Symptom Inventory scale on a touch-screen device, measure their body weight using a Bluetooth scale and record their circadian rest-activity rhythm using an infrared wrist-watch accelerometer over 6-weeks. The data are transmitted to the platform, then to a web portal with secured access to be daily inspected by the oncology nursing and medical team. The modelling of these continuous records will define alert thresholds for nurse-controlled graded intervention decisions. Conclusion: The assessment criteria set forth for the inCASA solution will address the issues of pt autonomy, CTS entrainment in the pt usual environment, safety of chronotherapy delivery at home and treatment costs. Its use should induce important organisational changes and perception in healthcare professionals.

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