The drying up of the Aral Sea has been described as one of the most staggering environmental disasters of the twentieth century. Over the last 40 years over 36 000 km 2 of the former seabed have been exposed, creating a potentially significant aeolian dust source. It is widely believed, but little researched, that increased dust storm activity in the region has had a major impact on human health. In this paper we report the findings of a study into the link between dust exposure and respiratory health amongst children in the Autonomous Republic of Karakalpakstan, Uzbekistan located on the southern shore of the Aral Sea. The findings indicate that dust deposition rates across the region are high, with sites located near the former shore of the sea being the worst affected. For these northerly regions the former bed of the Aral Sea is the most likely source of dust. The situation for the rest of the country appears to be far more complex. In these regions it appears that local sources and more distant sources to the south and south-west represent significant sediment providers, particularly in the early summer. Provisional analysis of the respiratory health data suggests that children living in the north of the country, where aeolian dust deposition rates are greater, show a lower frequency of respiratory problems. This inverse relationship requires further investigation, but highlights the complexities of environmental and human health inter-relationships.
The prevalence of asthma is low in the Aral Sea area and appears to be unrelated to dust exposure. Exposure to dust did not explain the main variations in lung function between geographical regions but high levels of dust exposure during the summer may have an adverse effect on lung function.
The importance of cues signaling reward, threat or danger would suggest that they receive processing privileges in the neural systems underlying perception and attention. Previous research has documented enhanced processing of motivationally salient cues, and has pointed to the amygdala as a candidate neural structure underlying the enhancements. In the current study, we examined whether the amygdala was necessary for this emotional modulation of attention to occur. Patients with unilateral amygdala lesions and matched controls completed an emotional attentional blink task in which emotional distractors impair the perception of subsequent targets. Emotional images proved more distracting across all participant groups, including those with right or left amygdala lesions. These data argue against a central role for the amygdala in mediating all types of attentional capture by emotional stimuli.
Previous research has indicated that the amygdala is a critical neural substrate of the emotional modulation of attention. However, a recent case-study suggests that the amygdala may not be essential for all types of emotion-attention interactions. In order to test this hypothesis, we assessed the visual-search performance of patients with unilateral amygdala lesions, matched controls, and medication-matched epilepsy patients with intact amygdalae. All participants completed a visualsearch task consisting of trials in which (1) an emotional target was embedded amongst neutral distractors, (2) a neutral target was embedded amongst emotional distractors, or (3) a neutral target was embedded amongst neutral distractors. All participant groups, including those with amygdala lesions, detected emotional targets more efficiently than neutral targets. These data indicate that the amygdala is not necessary for emotion-guided visual search and suggest that other mechanisms beyond the amygdala help guide attention toward threatening stimuli.
Afghanistan's health system is severely limited in terms of preventive and curative services, referral systems, and human resources. Most of the country's citizens reside in rural areas, a majority of which are served by "basic health units" (small and simple facilities that provide primary care), and these rural residents face additional challenges regarding timely access to quality health care. The analysis described in this article, which focuses on data derived from 2 rural health units during a 1-year period, revealed that infectious diseases, mainly acute respiratory infections, were a primary concern and that there is a clear need for increasing access to health services. In addition, our results showed that women are underrepresented as patients and appear to be at higher risk than men of tuberculosis.
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