The present study demonstrates an innovative approach of utilizing high‐pressure torsion (HPT) processing for the mechanical bonding of dissimilar metals during the microstructural refinement process. This processing approach has been developed recently for introducing unique alloy systems with improving physical and mechanical properties. Accordingly, the present study focuses specifically on the microstructural evolution and development in micro‐mechanical responses in the mechanically bonded Al‐Mg and Al‐Cu hybrid alloy systems when synthesized by HPT processing for very high number of turns up to 60 under 6.0 GPa at room temperature. The microstructural and hardness evaluations confirm the capability of the HPT procedure for the formation of heterostructures with extreme hardness at the disk peripheries and with low hardness at the disk centers in these processed alloy systems. Nanoindentation measurements demonstrate that both hybrid alloy systems exhibit excellent plasticity at the disk edges, where the hardness is the highest. There is a considerable potential for applying the solid‐state reaction through the HPT process for the bonding of dissimilar metals as a manufacturing technique and for the development of hybrid alloy systems.

There is an increasing demand for ultrahigh-strength steel in automotive industries to facilitate the manufacture of lightweight vehicles without compromising their security features. Although transformation-induced plasticity and dual phase steels have strengths of under 1 GPa, boron-alloyed steel obtained after the hot-press process has a strength of over 1500 MPa. Al–Si-coated steel has been developed to prevent excessive oxidation during high-temperature processes, but the Al–Si coating is known to lower weld properties. In this research, the laser weldability of hot-press-forming steels with and without Al–Si coating was examined. The specimens were laser-welded in butt and overlap joints by using disk and fiber lasers. The influence of the process parameters on the weld strength was investigated.

Sensor Networks can perceive the extensive area by application of many sensor nodes because the size of sensor nodes is small and cheap. Sensor nodes can transfer multi hop data to sink nodes which is far away than sending and receiving distance. Many routing methods are proposed in order to raise energy efficiency in sensor networks filled. There is a routing method based on structure as a composing method of network by cluster. Cluster technology consisting and maintaining network topology based on cluster is mostly studied in routing protocol. There are demerits that LEACH, EACHS shall be rest energy of all nodes and HEED can't guarantee the number of cluster head. The proposed energy efficiency of selected cluster head guarantees the number of cluster head which is a demerit of HEED and minimizes the node of DEAD.

Liriope platyphylla (LP) has long been regarded as a curative herb for the treatment of diabetes, asthma, and neurodegenerative disorders. To examine the therapeutic effects of Red LP (RLP) manufactured by steaming process on neurodegenerative disorders, significant alteration of the key factors influencing Alzheimer's Disease (AD) was detected in NSE/hAPPsw transgenic (Tg) mice after RLP treatment. The concentration of nerve growth factor (NGF) in serum increased in RLP-treated NSE/hAPPsw Tg mice compared with vehicle-treated Tg mice. However, downstream effectors of the NGF receptor signaling pathway, including TrkA and p75NTR proteins, were suppressed in RLP-treated NSE/hAPPsw Tg mice. Especially, Tg mice showed decreased levels of TrkA, p75NTR, and RhoA expression. Production of Aβ-42 peptides was lower in RLP-treated NSE/hAPPsw Tg mice than in vehicle-treated Tg mice. Further, analysis of γ-secretase components showed that Aβ-42 peptide expression was downregulated. Of the four components, the expression of APH-1 and Nicastrin (NCT) decreased in RLP-treated NSE/hAPPsw Tg mice, whereas expression of PS-2 and Pen-2 was maintained or increased within the same group. Overall, these results suggest that RLP can help relieve neurodegenerative diseases, especially AD, through upregulation of NGF secretion ability, activation of NGF signaling pathway, downregulation of Aβ-42 peptide deposition, and alteration of γ-secretase components.

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Abstract:The present study investigates the significance of pre-strain on the T6 aging behavior of an Al 7075 alloy for evaluating the applicability of hot stamping. In practice, the alloy was pre-strained up to 15% during solution heat treatment at 480 • C prior to quenching, and artificial aging was conducted at 120 • C. The peak aging time and precipitation behavior were compared with the alloy with pre-straining at room temperature after quenching but immediately before the artificial aging. The results showed that increasing amounts of pre-strain tend to reduce the aging time up to 50% for achieving peak hardness, which is consistent with the alloy at the T6 condition. There is a limitation for the maximum attainable amount of pre-strain of 10% for the homogeneous distribution of strain when the alloy is strained at room temperature (RT) due to the low formability. The pre-strained alloy as hot stamping exhibited lowering of the peak reaction temperatures for dissolution and formation of Guinier-Preston (GP)-Zones and precipitated with increasing amounts of pre-strain towards 15% through the differential scanning calorimetry analysis, thereby confirming the shortening of the peak aging time. The present study confirms the excellent potential of the hot-stamping process to extend the capability of an Al 7075 alloy.

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