Preferred Reporting Items for Overviews of Reviews (PRIOR): a protocol for development of a reporting guideline for overviews of reviews of healthcare interventions

The synthesis and antirhinovirus activity of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine (4 and 5) are reported. The structural assignments of 4 and 5 are based upon 13C NMR spectra of both isomers and also X-ray analysis of 5. The anti-isomer 5 was more potent than the syn-isomer 4 when compared as an inhibitor of rhinovirus multiplication in vitro. Both isomers inhibited multiplication of 15 different serotypes of rhinovirus.

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Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli

Rao¹,

Allen²,

Hobbs³

et al. 1983

Antimicrob Agents Chemother

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An improved synthesis of homoproline and derivatives

Shuman¹,

Ornstein²,

Paschal³

et al. 1990

J. Org. Chem.

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The structure of A201A, a novel nucleoside antibiotic.

et al. 1985

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Jonathan W. Paschal

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Synthesis of syn and anti isomers of 6-[[(hydroxyimino)phenyl]methyl]-1-[(1-methylethyl)sulfonyl]-1H-benzimidazol-2-amine. Inhibitors of rhinovirus multiplication

Genetic and enzymatic basis of hygromycin B resistance in Escherichia coli

An improved synthesis of homoproline and derivatives

The structure of A201A, a novel nucleoside antibiotic.

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