Reduction of phosphine oxides into the corresponding phosphines using PhSiH3 as a reducing agent and Ph3C+[B(C6F5)4]− as an initiator is described. The process is highly efficient, reducing a broad range of secondary and tertiary alkyl and arylphosphines, bearing various functional groups in generally good yields. The reaction is believed to proceed through the generation of a silyl cation, which reaction with the phosphine oxide provides a phosphonium salt, further reduced by the silane to afford the desired phosphine along with siloxanes.
Urethanes synthesis via oxidative decarboxylation of oxamic acids under mild electrochemical conditions is reported. This simple phosgene-free route to urethanes involves an in-situ generation of isocyanates by anodic oxidation of...
The photosensitized p-anisaldehyde-mediated
addition
of sulfonylcyanides onto the π-system of cyclobutenes is shown
to afford highly functionalized cyclobutanes in high yields and diastereocontrol.
The homochiral cyclobutene precursors are accessible on multigram
scale in two steps through an asymmetric [2 + 2] cycloaddition/vinyl
thioether reduction sequence. The enantiopure cyclobutylnitriles can
be elaborated further through SmI2-mediated ring opening
or converted into new enantiopure cyclobutenes through base-mediated
sulfone elimination.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.