The results provide evidence for the ability of sertraline both to sustain improvement in PTSD symptoms and to provide prophylactic protection against relapse.

Only two out of the 15 studies reviewed were high in methodological quality and showed significant reductions in LBP intensity with exercise. Future research is needed to clarify which exercises are effective and the dose-response relationships regarding exercise and outcomes.

Testing large software packages can become very time intensive. To address this problem, researchers have investigated techniques such as Test Suite Minimization. Test Suite Minimization reduces the number of tests in a suite by removing tests that appear redundant, but risks a reduction in fault-finding ability since it can be difficult to identify which tests are truly redundant. We take a completely different approach to solving the same problem of long running test suites by instead reducing the time needed to execute each test, an approach that we call Unit Test Virtualization. We describe the empirical analysis that we performed to ground our approach and provide an implementation of Unit Test Virtualization targeting Java applications. We evaluated our implementation, VmVm, using 20 real-world Java applications and found that it reduces test suite execution time by up to 97% (on average, 62%) when compared to traditional unit test execution. We also compared VmVm to a well known Test Suite Minimization technique, finding the reduction provided by VmVm to be four times greater, while still executing every test with no loss of fault-finding ability.

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The clinical, endoscopic, and radiological features of seven patients with an uncommon oesophageal injury characterised by long lacerations of the oesophageal mucosa with haematoma formation but without perforation are reported. The injuries were not related to forceful vomiting or any other definable cause but were similar to those previously described as intramural oesophageal rupture. Upper gastrointestinal endoscopy undertaken to identify the cause of haematemesis in six patients proved safe and useful. When dysphagia and odynophagia occurred early in the clinical course to alert the clinician to possible oesophageal injury, radiological contrast studies were used to exclude perforation. One patient in this study had oesophageal cavernocapillary haemangiomatosis which may have caused intramural oesophageal bleeding and submucosal dissection but in the remainder the aetiology of intramural oesophageal rupture remains uncertain. Conservative management was successful in ali patients.

The imaging features of astroblastoma are identified in 12 previously unreported cases. Distinguishing features that can be used to narrow the differential diagnosis with more common primary brain neoplasms reflect a combination of age, anatomic location, and specific imaging findings such as demarcation, heterogeneous tumor enhancement, rim enhancement, and a multicystic "bubbly" appearance. Intraventricular location, intratumoral hemorrhage with a fluid-fluid level, and dural "tails" are less common but important additions to the imaging spectrum.

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