Background: Malaria parasite has been observed to be a common infection in Human Immunodeficiency virus (HIV), an increase malaria infection in adults. Objective: This experimental study is sets to determine the prevalence and density of malaria parasitaemia in Warri com- munity, South-Southern Nigeria. Methods and Results: A total of 600 participants were screened for Human immunodeficiency virus and malaria parasite using WHO systems two and Geimsa staining technique for thick and thin blood films and absolute parasite counts done respectively. The prevalence rate of 38% and 39% were obtained for malaria parasite infection among HIVSP and HIV/ span>SN respectively. The difference in malaria parasite infection was not statistically significant (P>0.05) between HIVSP and HIVSN. However, the mean parasite density in HIVSP was significant (P<0.05) when compared with HIVSN. The mean parasite densities of 2384 ± 747 and 1883 ± 645 were recorded for HIVSP and HIVSN respectively. The mean par- asite densities of 2385 ± 782 and 2383 ± 717 observed for males and females respectively showed no statistical significant difference (P<0.05). Conclusion: This study has shown a high prevalence of malaria parasite among the HIV infected subjects. Keywords: Density; Malaria; HIV; prevalence; Nigeria.
Objective: To determine the effect of Cnestis ferruginea Vahl ex DC (connaraceae) root bark extract on gastrointestinal tract (GIT) microbiome of Albino wistar rats. Materials and Method: A total of 15 wistar rats were used for this study. They were randomly divided into 5 groups. Fecal samples were collected, a 10 fold serial dilution was done and plated using a spread plate method. The powdered root bark of Cnestis ferruginea was extracted with 80% methanol using a soxhlet extractor at 60°c. The resulting extract was administered to the rats in different doses, 200 mg/kg body weight (low dose) and 400 mg/kg body weight (high dose) for 14 days. Results: The study revealed that at both low and high doses, the root bark extract of C. ferruguinea was able to reduce the population of the bacteria present in the GIT of the Wistar rats with only providencia, Aeromonas spp, and Proteus spp as remaining organisms when compared to the control group, thus confirming the antimicrobial effect of the root extract.
The effect and extent of changes in some biochemical parameters associated with pneumonia caused by Staphylococcus aureus were investigated in serum samples of Wistar rats. 0ne thousand five serum samples were collected randomly. The serum samples were tested for sodium, potassium, urea, creatinine and chloride by colorimetric methods. The concentrations of sodium ranged from 133.6±4.615 to 143.8±6.906, potassium values ranged from 5.78±1.26 to 8.02±0.779, urea gave a range of 10.143±0.69 to 14.444±2.404, chloride values ranged from 94.8±2.683 to 104.142±8.49, while creatinine values ranged from 0.489±0.033 to 1.7±2.404. The results indicated that Staphylococcus aureus has a significant effect on the electrolyte balance causing hyperkalemia and hyponatremia when compared to normal blood value. It had a remarkable effect on creatinine level with only slight effect on urea. There is need to monitor the electrolyte levels in Staphylococcus aureus infection since alteration in the electrolyte levels could be harmful to health.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.