This study extended Brown and Levinson's model of politeness in order to explain more complicated forms of interaction and proposed three different types of f a m o r k : solidarity, approbation, and tact. The effects of three social factors-relational intimacy, power difference, and the right to perform a given act in a given situation-on the three types of facework were examined. Relational intimacy was the strongest positive predictor of facework. Its effect was consistent across different types of facework and across different levelsofpowerandright. 77w right toperforma certainactandspeaker'spowerdecreased facework, but these effects were mediated by relational intimacy, achieving significance mainly in distant relationships. The study also examined the relationships among different types offacework. Respondents used multiple types of facework when multiple face wants were threatened, and the use of one type of facework did not decrease the use of other types.esearch by a number of scholars (e.g.R 1987; Tracy, 1983) has attempted to explain people's selection of communicative strategies in terms of facework (Goffman, 1967). The model of politeness proposed by Levinson (1978,1987) has attracted particular attention from these researchers. However, communication studies based on Brown and Levinson generally found that the model could not adequately explain people's facework in communicative interaction. In this study, we extend Brown and Levinson's politeness model to explain various types of facework performed by communicators. In the process, we address several conceptual problems in Brown and Levinson's model includ-

High-field proton magic-angle sample-spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is shown to yield high-resolution 'H spectra of smectic, nematic and hexagonal-I1 phase lipids, from which isotropic chemical shifts, order parameters and relaxation times (q, qp and T,) can be determined. Such experiments are possible because of the special form of the dipolar Hamiltonian in such systems. Resolution is about the same as that obtained with sonicated systems, using conventional NMR techniques. We also show that 13C MAS NMR spectra, of both fluid and solid phases, are even better resolved, and in some cases resonances can be observed in MAS NMR spectra which are not observable in sonicated systems. For example, essentially all of the carbon atoms in cholesterol (CHOL) can be readily detected and assigned in a lecithin-CHOL bilayer, using MAS, while few can be seen in sonicated bilayers. This leads directly to the observation of cholesterol in intact biological membranes, such as human myelin, where over 50 peaks can be observed, and ca. 40 of these resonances can be assigned to specific, single-carbon-atom sites in the membrane. In addition, a number of experiments with massively deuterated lipids are reported. Combination of cross-polarization techniques with MAS, and difference spectroscopy, leads to the observation of essentially pure sterol spectra (in the presence of lipid) and pure lipid spectra (in the presence of CHOL). Analysis of chemical-shift results indicates a substantial deshielding of chain carbon atom resonances caused by the presence of CHOL, due presumably to increased trans chain segments, an effect mirrored in variable temperature spectra of human myelin, and in goldfish myelin. Taken together, these results suggest a resurgence in NMR studies of membranes may soon occur.

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This meta-analysis examines the five factors from the Relational Maintenance Strategies Measure (RMSM, i.e., positivity, openness, assurances, social networks, and sharing tasks) and their associations with satisfaction, commitment, control mutuality, love, liking, and relationship duration. Across 35 studies (N ¼ 12,273 participants), results showed positive correlations between the maintenance factors and the relational correlates except relationship duration, which was negatively associated with positivity and assurances and unassociated with openness, social networks, and sharing tasks. Moderator analyses showed differences in effect sizes depending upon measure (i.e., RMSM or a revision), reporter (i.e., perceptions of partner's maintenance or individuals' own enactment of maintenance), and biological sex. Effect sizes were generally larger for women than men and when studies used the RMSM and perceptions of the partner's maintenance.

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The chemical shifts of 31P and 1H in thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) (TmDOTP5-) are approximately two orders of magnitude more sensitive to temperature than are water proton and 19F shifts. In the physiologically relevant pH range, the 31P and 1H chemical shifts of TmDOTP5- are linear functions of temperature between 25 and 47 degrees C. The results indicate that using TmDOTP5- can provide measurements of temperature in vivo that are significantly more accurate than methods based on water and fluorocarbon chemical shifts.

The effect of ranitidine in preventing mucosal damage caused by nonsteroidal antiinflammatory drugs (NSAIDs) was evaluated for eight weeks in a prospective study of 144 patients requiring NSAIDs. Patients with normal endoscopic findings were randomly assigned to receive either ranitidine 150 mg twice daily or placebo for eight weeks, along with either ibuprofen, indomethacin, naproxen, sulindac, or piroxicam. Duodenal damage was significantly less in the ranitidine group compared with the placebo group by weeks 4 and 8 (P less than or equal to 0.01). Duodenal ulcers did not develop in any patients on ranitidine (0/57) compared with 4/49 patients (8%) on placebo (P = 0.02). No significant difference was found between treatment groups with respect to gastric damage; 6/60 (10%) in the ranitidine group compared with 6/50 (12%) in the placebo group developed gastric ulcers. These findings suggest that acid suppression is of greater importance for mucosal protection in the duodenum than in the stomach, where other defense mechanisms may be operative. While ranitidine is an effective prophylaxis for NSAID-induced damage in the duodenum, further studies are needed to define specific risk groups and to assess the potential usefulness of more complete acid suppression in preventing gastric mucosal damage.

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