Digoxin is a commonly prescribed medication for a variety of cardiovascular abnormalities. The therapeutic index of digoxin is considered narrow and drug is absorbed predominantly from the duodenum and upper jejunum. When the small intestine is intact, the absorption can vary; therefore, in the case of a small bowel resection or bypass, this erratic absorption may be accentuated. There is some controversy concerning the effect of small bowel resection or bypass on the absorption of digoxin. Some investigators have shown that small bowel resection or bypass decreases the absorption of oral digoxin, whereas others report no change in absorption. When the study methodologies were evaluated, certain common factors that support each view were found. In most studies reporting malabsorption, a solid dosage form of digoxin was used. Studies reporting no change in absorption investigated a solution dosage form.
The main objective of this study was to determine the relationship between occurrence of malaria infection with that of human blood group in Dares -Salaam Tanzania. The study was based on data collected randomly from the patients who were screened for malaria of all age groups for a period of three months at Mission Mikocheni Hospital. During this time period, a total of 430 blood samples were collected. From the study findings, it is clear that more than 50% of the patients tested were positive for malaria. Further analysis revealed that about 50% of malaria positive patients were type "O" blood group.
The emergence of the Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) pneumonia, also referred to as COVID-19 in New York City in March 2020, has put an overwhelming strain on the healthcare system in the city. Many local hospitals have reported a surge of cases, with most cases presenting with severe respiratory complications. We aim to present a comprehensive surge filter protocol for outpatient programs to mitigate the surge of cases admitted in the emergency rooms and intensive care units (ICUs) of local hospitals in our community. Our surge filter protocol was developed based on a detailed review of how South Korea and Spain mounted their outpatient surge responses. Our preliminary findings revealed that our Four-Ts approach (i.e., Test, Treat, Track, and Teach) has resulted in none of our patients reaching a clinical requirement for inpatient care.
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