Introduction Vaginal laxity is increasingly recognized as an important condition, although little is known regarding its prevalence and associated symptoms. Aim To report the prevalence of self-reported vaginal laxity in women attending a urogynecology clinic and investigate its association with pelvic floor symptoms and female sexual dysfunction. Method Data were analyzed from 2,621 women who completed the electronic Personal Assessment Questionnaire-Pelvic Floor (ePAQ-PF). Main Outcome Measure Response data from ePAQ-PF questionairre. Results Vaginal laxity was self-reported by 38% of women and significantly associated with parity, symptoms of prolapse, stress urinary incontinence, overactive bladder, reduced vaginal sensation during intercourse, and worse general sex life (P < .0005). Clinical Implications Clinicians should be aware that vaginal laxity is prevalent and has an associated influence and impact on sexual function. Strength & Limitations The main strength of this study is the analysis of prospectively collected data from a large cohort of women using a validated questionnaire. The main limitation is lack of objective data to measure pelvic organ prolapse. Conclusion Vaginal laxity is a highly prevalent condition that impacts significantly on a woman’s sexual health and quality of life.

This study provides insight into NE, a commonly reported symptom in women attending urogynaecology clinics. To our knowledge, this is the first study to implicate stress incontinence as an important aetiological factor in women with NE. Further studies are required to better understand the aetiology of NE in adult women and relate this to management and outcome.

Pelvic organ prolapse (POP) is a common condition for which the estimated lifetime risk of undergoing surgery is 12.6% [1]. Despite the global rise in the prevalence of obesity, defined as body mass index (BMI) greater than or equal to 30 kg/m 2 , little

Background Despite consistently low bleeding rates in laparoscopic cholecystectomy (LC) (0.1 – 0.46%), preoperative testing of ABO group and Rh (D) – G&S – remain common practice throughout UK hospitals. Current NICE guidelines for routine pre-operative tests for elective surgery don't include routine G&S. Additionally, there have been few recently published articles regarding elective and emergency LC suggesting that the routine practice of G&S are unnecessary, potentially delaying surgeries with significant financial impact. Based on published data, if a patient undergoing LC requires perioperative blood transfusion there is no time to cross match, therefore the major hemorrhage protocol is activated and patient is transfused O negative. Aim This project aimed to assess the need for routine G&S in laparoscopic cholecystectomy including impact on Trust resources, national shortage of blood tubes. Methods Retrospective data collection regarding 448 patients that underwent LC at Northern General Hospital, Sheffield in 2020. Results Between January and December 2020 401 G&S samples were taken during the preoperative assessment, and 425 second G&S samples taken on the day of surgery. Antibodies were identified in 8 patients, although they were not cross matched. Furthermore, none of the 448 patients required blood transfusion during the perioperative period. Conclusions Our results highlight that current compliance with NICE guidelines/recent published data is suboptimal. Overall, collecting G&S samples perioperatively takes up resources, time and can delay surgery. Furthermore, Trust savings could be in excess of £8000 in one year. Hence, we are currently reviewing our local policy.