Objective:Characterization of magnetic (MRI) features in women undergoing uterine fibroid embolization (UFE) and identification of clinical correlates in an African population.Materials and Methods:Patients with symptomatic fibroids who are selected to undergo UFE at the hospital formed the study population. The baseline MRI features, baseline symptom score, short-term imaging outcome, and mid-term symptom scores were analyzed for interval changes. Assessment of potential associations between short-term imaging features and mid-term symptom scores was also done.Results:UFE resulted in statistically significant reduction (P < 0.001) of dominant fibroid, uterine volumes, and reduction of symptom severity scores, which were 43.7%, 40.1%, and 37.8%, respectively. Also, 59% of respondents had more than 10 fibroids. The predominant location of the dominant fibroid was intramural. No statistically significant association was found between clinical and radiological outcome.Conclusion:The response of uterine fibroids to embolization in the African population is not different from the findings reported in other studies from the west. The presence of multiple and large fibroids in this study is consistent with the case mix described in other studies of African-American populations. Patient counseling should emphasize the independence of volume reduction and symptom improvement. Though volume changes are of relevance for the radiologist in understanding the evolution of the condition and identifying potential technical treatment failures, it should not be the main basis of evaluation of treatment success.
A 38-year-old male soldier presented to the accident and emergency unit with generalized malaise, yellowing of the eyes, and constipation for 3 months. Laboratory tests (reference range in parentheses) revealed: positive hepatitis B surface antigen; elevated hepatitis B viral load of 14,023,079; alpha-fetoprotein levels of 156,660 ng/ml (0–7); direct serum bilirubin of 56.90 mmol/l (0–3.4); total serum bilirubin of 77.90 mmol/l (0–21); gamma GT of 458 u/I (0–60); alkaline phosphatase of 385 u/I (30–120); aspartate aminotransferase of 285 u/I (0–50); and alanine aminotransferase of 120 u/I (0– 50). Hepatitis C antibody and HIV I and II ELISA tests were negative
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