We investigated the factorial composition as well as the demographic, anamnestic and clinical correlates of 13 features of delusional beliefs in a sample of 127 psychiatric inpatients with active delusions at the time of their assessment: Six factors were extracted, jointly accounting for 67.3% of the variance, which were interpreted as the dimensions of cognitive disintegration, volitional dyscontrol, doxastic strength, distress, incongruence and expansiveness, respectively. Moreover, most factors exhibited distinctive profiles of demographic, anamnestic or clinical correlates. Overall, our findings provide supportive evidence for both the clinical multidimensionality of delusional beliefs at the factor-analytic level and the – at least partial – external validity of the factorial solution obtained.

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lasma prolactin levels and responses to i. m. haloperidol of patients on treatment with antipsychotic drugs, reflect the prolactin release potencies of the drugs, which are related, but not restricted, to their affinities to D2 dopamine receptors. According to the prolactin baseline levels and responses to i. m. haloperidol, the drugs of this study can be categorized for their potency to the pituitary dopamine system that controls prolactin release, as follows: sulpiride > risperidone > haloperidol > olanzapine > clozapine. This categorization is similar to that obtained by binding studies in striatal D2 dopamine receptors using brain imaging techniques.

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