No abstract

OXONE over silica gel or, in some cases, alumina has been found to oxidize the primary and secondary amines 3 selectively to the corresponding hydroxylamines 4, in either the presence or absence of a solvent. Treatment of Boc-protected L-lysine (6) under the latter conditions afforded hydroxylamine 7 in excellent yield. The trialkylamine 1a and pyridine (1b), in which selectivity is not an issue, were readily oxidized to the corresponding oxides 2 by OXONE over silica gel or alumina, as well as by (CH(3))(3)COOH over silica gel. Solvent-free oxidation assisted by microwave irradiation was more forcing, while still affording the hydroxylamines 4 selectively, and is the synthetic method of choice. The mechanistic aspects of these reactions are discussed.

No abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

No abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

The substituted acetic acids (I) are coupled with propionaldehyde (II) and then cyclized, yielding the β‐lactones (IV) via (III).

If the ratio were exactly four zinc to three manganese, using the most recent atomic weights, the strength of this solution against manganese mould be one cc. = 0.00382 gram, while, according to Wyrouboff, IoMn = gK,Fe(CN) , and 6Zn = 4K,Fe(CN),, or IoMn= 1 3. j Zn, or r M n = 1.35 Zn, and the strength against manganese would be I cc. = 0.003774 gram.