In order to create innovative pathways to services and resources, the authors propose placing a "game-layer" on top of the library, luring new patrons with the potential of playing an Alternate/Augmented Reality Game (ARG). Using both physical and virtual library space a variety of "nodes" are created, drawing players to various library locales even regular patrons may be unfamiliar with and presenting them with story fragments and puzzles. Each node requires players to use library resources like databases and books, or engage library staff at known service points in order to move forward. Players contribute to the game itself in the form of puzzle solutions. Far more illustrative than a guided tour or required course/class, this library ARG encourages players to discover and utilize resources within the context of the game, generating fluency in library systems, places and platforms. But more importantly, the ARG invites a process of "meta-level reflection" invaluable throughout a patron's academic career.
Canceling the Big Deal is becoming more common, but there are still many
unanswered questions about the impact of this change and the fundamental shift in the
library collections model that it represents. Institutions like Southern Illinois
University Carbondale and the University of Oregon were some of the first institutions
to have written about their own experience with canceling the Big Deal several years
ago, but are those experiences the norm in terms of changes in budgets, collection
development, and interlibrary loan activity? Within the context of the University of
California system’s move to cancel a system-wide contract with Elsevier, how are
libraries managing the communication about Big Deals both internally with library
personnel as well as externally with campus stakeholders? Three R1 libraries (University
of Maryland, University of Oklahoma, and Kansas State University) will compare their
data, discuss both internal and external communication strategies, and examine the
impact these decisions have had on their collections in terms of interlibrary loan and
collection development strategies. The results of a brief survey measuring the status of
the audience members with respect to Big Deals, communication efforts with campus
stakeholders, and impacts on collections will also be discussed.
Microsymposia increase enzymatic activity. The structure suggests that interaction with the membrane is mediated by one of the p85 domains (iSH2). The existence of p110alpha gain-of-function-mutants makes this protein an attractive therapeutic target. Since PI3Ks control a wide range of physiological functions, it would be desirable to inhibit only p110alpha, the isoform mutated in cancers. Structural differences among the isoforms can be exploited for that purpose. These findings may provide not only novel insight for the design of PI3K-isoformselective drugs but also help on the design of mutation-specific drugs.
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