The Hamilton Program for Schizophrenia Voices Questionnaire (HPSVQ) was developed to address the need for a brief, self-report measure that quantifies a range of the characteristics of auditory verbal hallucinations (AVHs). Each of the questionnaire's nine scored items utilizes a 5-point rating scale to yield a quantitative assessment of AVHs. The scale was well tolerated by a sample of 20 patients with schizophrenia and schizoaffective disorder at baseline and at one and eleven weeks postbaseline. It demonstrated good test-retest reliability over these intervals and good internal consistency. In addition, it demonstrated adequate concurrent validity when compared with the interviewer-rated Psychotic Symptoms Rating Scales Auditory Hallucinations subscale. The results of this pilot study suggest that the HPSVQ is potentially a reliable and useful measure for quantifying AVHs in persons suffering from psychosis.
ResumeLe Hamilton Program for Schizophrenia Voices Questionnaire (HPSVQ) a ete CT€€ pour r^pondre a la n^cessit^ de posseder un instrument bref et auto rapporte qui puisse quantifier une vari^t6 de caract^ristiques d'hallucinations audidvo-verbales. Les neuf items du questionnaire sont cotes selon une Echelle en 5 points, afin de mesurer la presence d'hallucinations auditivoverbales. Le questionnaire a ete bien toler^ par un groupe de 20 patients lors de la premiere application ainsi que lors des applications subsequentes, une et onze semaines plus tard. Le questionnaire demontre une bonne fid^lite test / retest lors de ces intervalles, ainsi qu'une bonne consistance interne. Le questionnaire demontre egalement une validity concomitante adequate avec le Psychotic Symptoms Rating Scale Auditory Hallucination tel qu'^valu^ par l'interviewer. Les resultats de cette 6tude-pilote indiquent que le HPSVQ constitue un instrument potentiellement valide et approprie pour ^valuer quantitativement la presence d'hallucinations auditivoverbales chez les patients atteints de psychoses.
A brief psychological screening test, devised by Rey (1964), was developed to assess the validity of memory complaints. Although Rey hypothesized that malingerers would be misled to perform poorly while even individuals with severe concentration problems could succeed, a review of the literature did not reveal any empirical reports that examined the actual performance of nonmalingering though disturbed patients. Therefore, Rey's test was administered to samples of acutely disturbed psychiatric patients (N = 50) and intellectually deficient individuals (N = 16). The results confirmed the criterion proposed by Lezak (1983) and suggested that malingering should be considered among individuals who deny remembering at least 9 of the 15 times of the Rey test.
A number of studies suggest anterior cingulate cortex (ACC) abnormalities in autism spectrum disorder (ASD), which might underlie response monitoring and social impairments exhibited by children and adolescents with ASD. The goal of the present study was to extend this work by examining error and correct response monitoring using event-related potentials (ERN, Pe, CRN) and LORETA source localization in high functioning adults with ASD and controls. Adults with ASD showed reduced ERN and Pe amplitudes and reduced rostral ACC activation compared with controls. Adults with ASD also showed less differentiation between error and correct ERP components. Social impairments and higher overall autism symptoms were related to reduced rostral ACC activity at the time of the ERN, particularly in adults with ASD. These findings suggest that reduced ACC activity may reflect a putative brain mechanism involved in the origins and maintenance of social impairments and raise the possibility of the presence of stable brain-behavior relation impairment across development in some individuals with ASD.
The present experiment eliminated the contribution of perceptual review to negative priming and demonstrated that when a pure measure of inhibition is taken on a localization task, patients with schizophrenia were less able to inhibit irrelevant distracting stimuli. The fact that NP was reduced in a spatial task suggested a more diffuse reduction in inhibition than previous studies that examined only identification-based responses.
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