Patients with sickle cell disease are known to have recurrent lower extremity ulcers that have a high pain score and are resistant to conventional means of wound therapy. This study reports the successful use of synthetic heparan sulphate (Cacipliq20(®) , OTR3, Paris, France) in the treatment of a sickle cell ulcer that had failed to respond to several other means of treatment. Therapeutic success was assessed by complete wound coverage and vast improvement in pain score. This is the first study to report use of heparan sulphate in sickle cell ulcers.
Robotic surgery is an emerging technology that is conquering the surgery field by storm. It has found solid applications in general surgery, gynecological surgery, vascular surgery, and especially in urology and cardiothoracic surgery. Its application is however restricted in the various fields of plastic surgery. There is no doubt that robots have a potential to become an important toll in reconstructive plastic surgery, but the extent of their use in aesthetic surgery is constrained. A review of the literature showed that several centers are currently using surgical robots for reconstructive and microsurgery. Robotic surgery is feasible and technically advantageous, though very costly. There is a paucity of data however concerning the long-term benefits of robotics versus conventional techniques, and none regarding aesthetic surgery applications. We strongly believe that, without ignoring the tremendous potential benefits of robotic technology in many fields of plastic surgery, no machine, no matter how sophisticated it is, will ever succeed at replacing the artistic sense, feeling, and touch necessary to achieve beauty with harmonious proportions.
Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare and benign proliferative disease that affects histiocytes. Its etiology remains unclear. Rosai-Dorfman disease primarily affects lymph nodes with many extranodal manifestations present, including cutaneous, pulmonary, ophthalmic, and gastrointestinal. Diagnosis is mainly histologic with the presence of Rosai-Dorfman cells, which demonstrate emperipolesis. We report a case of a 30-year-old man who presented with a facial cutaneous mass and was diagnosed with RDD; he underwent surgical excision. The patient experienced recurrent lesions on the surgical scar and parotid gland as well as the lower back. Treatment consisted of systemic steroids and surgical excision.
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