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Social isolation (SI) can have negative effects on health, although little is known about the SI consequences on patients with grade III obesity and even less if they are entering a prehabilitation program. Objective: the present study analyzes the effects of SI determined by the SARS-CoV-2 pandemic in people with grade III obesity who about to enter a prehabilitation program for bariatric surgery. Methods: Five patients with grade III obesity who entered a prehabilitation program or which had to be stopped on March 17th, 2020 were evaluated. Excessive daytime sleepiness (EDS) (Epworth Sleepiness Scale - ESS) and sleep quality (SQ) (Pittsburgh Sleep Quality Index - PSQI) were investigated. Data collection took place in the week before the SI government decree and after 30 and 90 days of SI. Statistical analysis was performed using SPSS 20.0 and GraphPad Prism 8.0. The Friedman test was used to verify the difference between the times and a significance level of p < 0.05 was adopted. Results: with SI, EDS improved by 8 points after 30 days and 3 points after 90 days (p < 0.05). The PSQI did not change (p = 0.819). Conclusion: the SI improved the EDS of individuals with grade III obesity entering the prehabilitation program, but did not change complementing their SQ. The improvement in EDS may be related to a longer daily sleep time provided by the SI and the lower number of daily work commitments. Measures to improve the SQ of these patients should be considered, including remote forms.

BackgroundRheumatic and musculoskeletal diseases (MSKD) are a prevalent leading cause of disability and consume a large amount of healthcare and social resources. MSKD have been associated with low levels of physical and mental health in other countries.ObjectivesTo estimate the national prevalence of hand, knee and hip osteoarthritis (OA), low back pain (LBP), rheumatoid arthritis (RA), fibromyalgia (FM), gout, spondyloarthritis (SpA), periarticular disease (PD) systemic lupus erythematosus (SLE), polymyalgia rheumatica (PMR) and osteoporosis (OP)) in the adult Portuguese population; to compare physical and mental health between participants with and without MSKD.MethodsEpiReumaPt is a national health survey conducted from Sep'2011 to Dec'2013, which involved a three-stage approach. First, 10661 adult subjects were randomly selected. Trained interviewers undertook structured face-to-face questionnaires in participant's households that included a screening for MSKD, and the EQ5D and HAQ. Secondly, all participants screened positive for at least one MSKD plus 20% of individuals with no rheumatic complaints were invited to be seen by a rheumatologist at the local Primary Care Center for a structured evaluation. Finally, a team of 3 experienced rheumatologists revised all the clinical data and confirmed the diagnoses according to previously validated criteria. Estimates were computed as weighted proportions, in order to take into account the sampling design.ResultsPrevalence of MSKD in the adult Portuguese population is presented in Table 1 with 95% CI. After adjustment, subjects with RMD had significantly lower EQ5D scores (β=-0.09; p<0.001) and higher HAQ scores (β=0.12; p<0.001) than subjects with no MSKD. Some MSKD were significantly and independently associated with worse EQ5D scores: PMR (β=-0.334), RA (β=-0.132), FM (β=-0.100), LBP (β=-0.07), Knee OA (β=-0.06) and PD (β=-0.04).Proportion of anxiety and depression symptoms among the MSKD Portuguese patients was 16.7% and 8.3%, respectively; the prevalence of anxiety symptoms was significantly higher when compared with subjects without MSKD diseases (OR=3.4; p=0.003). Moreover, FM (OR=3.12; p<0.001), SpA (OR=2.82; p=0.012) and LBP (OR=1.84; p=0.007) were significantly and independently associated with the presence of anxiety symptoms; PMR (OR=18.81; p=0.006), FM (OR=3.73; p=0.001) and LBP (OR=1.55; p=0.030) were significantly and independently associated with the presence of depression symptoms.ConclusionsMSKDs are highly prevalent in Portugal and are associated with significant impairment of physical and mental health.Disclosure of InterestJ. Branco: None declared, A. Rodrigues: None declared, N. Gouveia: None declared, L. Pereira: None declared, M. Eusébio: None declared, S. Ramiro: None declared, P. Machado: None declared, A. Mourão: None declared, I. Silva: None declared, P. Laires Employee of: Merck, A. Sepriano: None declared, F. Araújo: None declared, S. Gonçalves: None declared, P. Coelho: None declared, V. Tavares: None declared, J. Cerol: None declared...

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