No abstract

Ballistocardiography is a non-invasive technique that yields information about the cardiovascular system that is not available in other external signals such as the electrocardiogram (ECG). In the last years, several research groups have obtained the ballistocardiogram (BCG) by using instrumentation methods simpler than those available in the 1950s and that did not progress because of their complexity as compared to ultrasound and other noninvasive techniques that are in common use nowadays. We describe a novel method for real-time robust heart- (HR) and respiratory- (RR) rate detection from a subject that stands on a common electronic bathroom scale. BCG signals from the scale are wirelessly sent to a PC where algorithms based on the continuous wavelet transform (CWT) extract the HR and the RR. HR results are compared to those obtained from the ECG. To better assess the RR results, subjects have been asked to synchronize their breathing rate to an on-screen bar-graph set at a constant rate of breaths per minute. This method to obtain the heart and respiratory rates is simple, compact, non-invasive and passive, and can be applied to any person able to stand on an electronic weighing scale, even if wearing shoes.

Ab st ra c t -There is a growing interest in accurately measuring the timing of the J peak of the ballistocardiogram (BCG) in order to obtain cardiovascular function markers non-invasively, especially in modern home healthcare applications. In this paper we have studied the effect that some common uncertainty sources have in the time measurement of the J peak. This is a necessary step towards the standardization of modern ballistocardiography systems equivalent to that available for EGC systems. We conclude that, to reduce J peak time uncertainty below the measured intrinsic uncertainty of about ±2 ms, the minimal bandwidth should be from 1.5 Hz to 22.5 Hz; the sampling frequency can be decreased up to 50 Hz when using cubic spline interpolation; 5 bits are required to quantify the signal, and signal-to-noise ratio (SNR) and signal-to-interference ratio (SIR) should be over 40 dB and 3 dB respectively. Ke ywo rd s: Ballistocardiogram, acquisition system, biomedical instrumentation, standardization.

Time intervals measured between the electrocardiogram (ECG), the photoplethysmogram (PPG) or the impedance plethysmogram (IPG), have long been used to noninvasively assess cardiovascular function. Recently, the ballistocardiogram (BCG) has been proposed as an alternative physiological signal to be used in time interval measurements for the same purpose. In this work, we study the behavior of the RJ interval, defined as the time between the R wave of the electrocardiogram (ECG) and the J wave of the BCG, under fast pressure changes induced by paced respiration and tracked by a beat-to-beat blood pressure (SBP and DBP) waveform monitor. The aim of this work is to gain a deeper understanding of these newly proposed time intervals and to further assess their usefulness to determine cardiovascular performance.

The Driven-Right-Leg (DRL) circuit has been used for about 50 years to reduce interference due to common-mode voltage in biopotential amplifiers in scenarios that range from fixed equipment supplied from power lines to battery-supplied ambulatory monitors, and for systems that use gelled, dry, textile, and capacitive electrodes. However, power-line interference models predict that for isolation amplifiers, currently mandated by safety standards, power-line interference can often couple mostly in differential mode rather than in common mode. In this work we analyze the effect of the DRL circuit in different ECG leads to elucidate its actual effect on power-line interference reduction. It turns out that that the DRL circuit, which effectively reduces common-mode interference, affects differential-mode interference in an unpredictable way and can increase interference.

A novel algorithm JDet for ballistocardiogram (BCG) cycle extraction is presented that is intended for the fast generation of ensemble averages in ambulatory scenarios where the ECG signal is not available. First, the sensitivity (Se) and positive predictivity (+P) of JDet are evaluated on recordings obtained from 14 healthy subjects that stood on a modified weighing scale, and the results are compared with those from BSeg++, a popular BCG cycle-extraction algorithm. Second, the signal-tonoise ratio (SNR) is calculated for ensemble averages generated by using JDet, BSeg++, and the ECG R-waves on recordings of different duration. The results show that JDet has higher Se and similar +P than BSeg++. Therefore, the quality of the ensemble averages generated from JDet can be comparable to those generated from the ECG, the only cost being a 25 % longer recording time.

This paper describes a novel method to estimate pulse arrival time (PAT) from the electrocardiogram (ECG) and the impedance plethysmogram (TPG) obtained by using a compact and easy-to-use handheld device with only four electrodes. A proof-of-concept has been carried out where PAT values obtained with the proposed device have been compared to PAT values measured between the ECG and the photoplethysmogram (PPG) during three experiments of paced respiration to induce controlled PAT changes. The results show that both methods yield equivalent PAT values in within ± 7 ms (95 % confidence interval), which is less than typical deviations reported for common PAT measurements.

We present a novel method to detect proximal volume changes based on the impedance plethysmogram (IPG) measured from limb to limb with two electrode pairs symmetrically placed at distal areas of the upper or the lower limbs. Since the measurement is sensitive to changes along the whole current path, this method allows us to detect changes in arteries that are more proximal to the torso than the measurement sites. Our results show that the Pulse Arrival Time (PAT) measured from the R peak of the ECG to the hand-to-hand IPG is close to the PAT to the elbow whereas the PAT measured from the R peak of the ECG to the foot-to-foot IPG is close to the PAT to the knee. This opens new avenues for noninvasive cardiovascular measurements based only on electrodes in contact with hands or feet.