OBJECTIVETo investigate the association of preconception counseling with markers of care and maternal characteristics in women with pregestational diabetes.RESEARCH DESIGN AND METHODSThe study includes data from a regional multi-center survey on 588 women with pregestational diabetes who delivered a singleton pregnancy between 2001 and 2004. Logistic regression was used to obtain crude and adjusted estimates of association.RESULTSPreconception counseling was associated with better glycemic control 3 months preconception (odds ratio 1.91, 95% CI 1.10–3.04) and in the first trimester (2.05, 1.39–3.03), higher preconception folic acid intake (4.88, 3.26–7.30), and reduced risk of adverse pregnancy outcome (P = 0.027). Uptake of preconception counseling was positively associated with type 1 diabetes (1.87, 1.14–3.07) and White British ethnicity (2.56, 1.17–5.6) and negatively with deprivation score (0.78, 0.70–0.87).CONCLUSIONSEfforts are needed to improve preconception counseling rates. Uptake is associated with maternal sociodemographic characteristics.
Introduction
Fetal growth abnormalities are common complications of diabetes in pregnancy; there is little data on temporal trends in growth disturbance.
Aim
To determine changes in rate of large for gestational age (LGA) and small for gestational age (SGA) in babies of women with pre-gestational Type 1 or Type 2 diabetes (T1DM and T2DM).
Methods
Data were extracted from the Northern Diabetes in Pregnancy Survey, a register of pregnancies in women with pre-gestational diabetes resident in Northern England. We studied 1499 singleton live births delivered 1996–2008, excluding those with congenital anomalies. LGA was defined as birtweight >90th percentile for gestational age and SGA as<10th percentile, corrected for infant sex and parity.
Results
1164 (78%) women had T1DM and 328 (22%) T2DM; T2DM increased from 8.9% (1996–2000) to 32.1% (2005–2008) (p=0.01). Mean (SD) birth weight was 3437 g (±755). 335 (23%) babies weighed ≥4000 g. The rate of LGA was 49.3% and SGA 2.9% and did not change over time (LGA 50.9%, 1996–2000, 47.7%, 2005–2008; SGA 3.5%, 1996–2000, 2.9%, 2005–2008; p=0.73). LGA babies were more likely to be preterm (60.3% vs 37.2%, p=0.001), delivered by caesarean section (53.5% vs 43.3%, p=0.001), admitted to special care (56.5% vs 40.7%, p=0.001) and to develop shoulder dystocia (85.7% vs 11.9%, p= 0.001) than babies of normal weight for gestational age.
Conclusion
Rates of LGA and SGA have not changed over time despite an increase in T2DM.
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