Wageningen Centre for Development Innovation supports value creation by strengthening capacities for sustainable development. As the international expertise and capacity building institute of Wageningen University & Research we bring knowledge into action, with the aim to explore the potential of nature to improve the quality of life. With approximately 30 locations, 6,500 members (5,500 fte) of staff and 12,500 students, Wageningen University & Research is a world leader in its domain. An integral way of working, and cooperation between the exact sciences and the technological and social disciplines are key to its approach.
Detailed analyses of published trials conducted as part of a Cochrane review led to concerns over two trials conducted by a single author. The Cochrane team therefore requested a forensic analysis of all his published papers. Eleven papers were found. Where appropriate, pairwise comparisons were made of values in baseline and outcome tables, and p-values recalculated. The distributions of baseline characteristics were assessed for compatibility with properly conducted randomization using Monte Carlo analysis and unusual features noted. The analyses brought up several areas of concern; for instance, a high degree of identical or highly similar values in some baseline and outcome tables between studies; all recalculated p-values, save for one, are different from the p-values given; for all eleven studies, the probability that participants have been grouped according to properly randomised processes is very low. In correspondence with the author, he agreed that the sample we sent him showed that published p-values were incorrect, but was unable to provide original data to conduct further checks. We conclude that analyses of papers published by this author suggest considerable data concerns and that they should not be used to inform clinical practice until further investigation is completed.
Wageningen Centre for Development Innovation supports value creation by strengthening capacities for sustainable development. As the international expertise and capacity building institute of Wageningen University & Research we bring knowledge into action, with the aim to explore the potential of nature to improve the quality of life. With approximately 30 locations, 6,500 members (5,500 fte) of staff and 12,500 students, Wageningen University & Research is a world leader in its domain. An integral way of working, and cooperation between the exact sciences and the technological and social disciplines are key to its approach.
Wageningen Centre for Development Innovation supports value creation by strengthening capacities for sustainable development. As the international expertise and capacity building institute of Wageningen University & Research we bring knowledge into action, with the aim to explore the potential of nature to improve the quality of life. With approximately 30 locations, 6,500 members (5,500 fte) of staff and 12,500 students, Wageningen University & Research is a world leader in its domain. An integral way of working, and cooperation between the exact sciences and the technological and social disciplines are key to its approach.
Wageningen Centre for Development Innovation supports value creation by strengthening capacities for sustainable development. As the international expertise and capacity building institute of Wageningen University & Research we bring knowledge into action, with the aim to explore the potential of nature to improve the quality of life. With approximately 30 locations, 6,500 members (5,500 fte) of staff and 12,500 students, Wageningen University & Research is a world leader in its domain. An integral way of working, and cooperation between the exact sciences and the technological and social disciplines are key to its approach.
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