Comments Procedures for donors attention, registration, storage, transportation and milk collection from attention points to the Milk Bank should preserve the security and quality.The comparison of average acidity according to the origin of milk, coul be an adequate advisor in order to promote better strategies to minimise the percentage of rejected milk. Background To minimise extrauterine growth restriction in ELGANs computer assisted prescription of parenteral nutrition (CAPPN) was introduced. Aim To evaluate the effectiveness of CAPPN in growth improvement of ELGANs. Patients and methods In this retrospective, observational designed study with a nonprobability, convenience sampling to obtain medical records, we compared 20 ELGANs in the study group after CAPPN to 20 ELGANs in the control group before CAPPN. Daily parenteral and enteral intake of macronutrients, calcium and phosphate in five sequetial time intervals of the first 28 days of life was calculated (day 1-3, 4-7, 2nd, 3rd, 4th week). Outcome measures were the lenght of PN, days to regain birth weight (BW), growth velocity, and weight and head circumpherence (HC) <10th percentile on day 28. Numerical data were analysed by independent-samples t-test or by Mann-Whitney U test, categorical data were analysed by chi-square. Results The combined enteral and parenteral intake of the study group in all five sequential intervals after birth exceeded the intake of the control group. The lenght of PN and days to regain BW did not differ, however growth velocity (14,5 [3,7] Background and aim Studies in premature infants and animals show that carbohydrate malabsorption and gut microbiota colonisation are key elements for triggering necrotizing enterocolitis (NEC). Our aim was to determine how dietary carbohydrate composition affects the metabolomic profile and whether unique metabolite signatures correlate with NEC incidence. Methods Cecal contents and plasma were collected from a group of preterm pigs at birth and from three groups fed
PO-0607a
AbstractsBackground and Aims Parenteral nutrition (PN) is an integral part of neonatal intensive care, especially in the early nutritional support of very low birthweight (VLBW) newborns. However, it is associated with potentially serious complications such as sepsis and metabolic derangement. The aim of the study was to review PN use and complications in VLBW newborns at Royal Bolton Hospital with specific European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines as the standard. Methods PN use was reviewed in all VLBW newborns who received PN for more than 1 day during January 2009 to December 2010. ESPGHAN standards audited were the time of commencement of PN and composition of the PN bag. Results Of the 42 VLBW newborns included, the median gestational age and weight was 27 +0 weeks and 923g respectively. In this group, 24% of newborns met the ESPGHAN standard for amino acid commencement and 88% for lipid commencement. The glucose and phosphate content of the PN bag did not match ESPGHAN standards as the glucose content was higher and phosphate content lower than recommended. Most common PN complication was hyperglycaemia (64%), followed by hypophosphataemia (45%) and sepsis (38%). Coagulase negative Staphylococci were the most common organism cultured (94%). Conclusion There was a delay in commencement of PN. To achieve full compliance with ESPGHAN guidelines, amino acids and lipids should be commenced as recommended. Modifying constituents of the PN bag may help reduce complication rates of hyperglycaemia and hypophosphataemia.
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