Background. The Endoscopic sleeve gastroplasty (ESG) is one of the new advanced restrictive techniques of bariatric endoscopy. The principle of this bariatric technique is the reduction of stomach volume through endoscopic plication. The long-term efficacy and metabolic effects of this procedure are the subject of this study. Methods. 20 patients were enrolled; four men, sixteen women. Then they were followed for 24 months in terms of glycemic control, body composition, vitamin, and nutritional status. Observed parameters included glucose, triacylglycerols, high-and low-density lipoprotein cholesterol, micro and macro nutrients, fat mass, and lean body mass. Results. We observed significant weight loss and a decrease body composition resulted from procedure vs. baseline, with levels of blood glucose also showing statistically significant reductions. The most notable decline in measured values was observed in period six months after the procedure. No significant changes were observed in measurement of micronutrients. Conclusions. Good restriction results were obtained following ESG, which might be mediated via altered glucose metabolism. The ESG method has shown a positive effect on fat and muscle mass. Unlike surgical methods, there were no deficits or deficiencies, especially in terms of essential vitamin levels.
Introduction Pancreatic steatosis (PS) has both metabolic consequences and local effects on the pancreas itself. Magnetic resonance imaging (MRI) is the most reliable non-invasive method for diagnosing PS. We investigated the impact of metabolic syndrome (MS) on the presence of PS, differences in individuals with and without PS, and the metabolic effects of bariatric procedures. Methods Changes in anthropometric and basic biochemistry values and MS occurrence were evaluated in 34 patients with obesity who underwent a bariatric procedure. After the procedure, patients underwent MRI with manual 3D segmentation mask creation to determine the pancreatic fat content (PFC). We compared the differences in the PFC and the presence of PS in individuals with and without MS and compared patients with and without PS. ResultsWe found no significant difference in the PFC between the groups with and without MS or in the occurrence of PS. There were significant differences in patients with and without PS, especially in body mass index (BMI), fat mass, visceral adipose tissue (VAT), select adipocytokines, and lipid spectrum with no difference in glycemia levels. Significant metabolic effects of bariatric procedures were observed. Conclusions Bariatric procedures can be considered effective in the treatment of obesity, MS, and some of its components. Measuring PFC using MRI did not show any difference in relation to MS, but patients who lost weight to BMI < 30 did not suffer from PS and had lower overall fat mass and VAT. Glycemia levels did not have an impact on the presence of PS.
Jihočeská univerzita v Českých Budějovicích, Zdravotně sociální fakulta, katedra supervize a odborné praxe Summary Changes in the family life and its social and economic conditions can be currently observed, which exert principal effects on the demographic development. These conditions have subsequently adverse effects on the foundation of families. The motherhood and parenthood is a generally expected part of the human life and is associated with the period of maturity in the sense of the life contents and life tasks. The decision to have a child is currently quite not simple and social conditions and financial support of the family play important roles in considering the planned parenthood. The purpose of the research work was to find what social and economical changes occur in the family in association with the birth of a child-what is the extent and way of affecting the family life by the presence of the child. To obtain the data necessary for achieving the target, a method of inquiringquestionnaire-was used for the data accumulation. 170 respondents were contacted-parents on maternity or paternity leave, provided that 124 questionnaires were completely useful for the research. In all the cases these were women-mothers of childbearing age. 96% of respondents represented a complete family. The child in the family was their own, neither adopted nor in foster care. Within the framework of the research it was found that in association with the delivery of the child, social as well as economic situation of the family is changed and the parents assume a more difficult return to employment after the maternity/paternity leave. The results of the work demonstrated that the delivery of the child is not a simple problem for a number of couples. Conditions for the foundation of the family are quite not favourable.
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