This study explored the third-person effect in the context of direct-to-consumer (DTC) advertising. A survey of 264 adults examined perceptions of DTC ad effects and their relationship to support for DTC ad regulation. Results support the third-person-effect perceptual component. The study revealed that for DTC advertising, the third-person effect operates in a multidimensional fashion through four factors (Negative DTC Ad Effects, Learning and Involvement, Patient/Provider Interaction, and Distrust of DTC Ad Information)and that negative content-based third-person effects were greater than positive effects. However, the current study showed weak support for the thirdperson effect behavioral component. Only perceived self-effect for Distrust of DTC Ad Information and attitude toward DTC advertising were significant predictors of regulatory support. The findings are discussed in relation to existing theoretical work, and future research recommendations are provided.Empirical examinations of media message effects have been greatly influenced by the third-person effect hypothesis. Since Davison first introduced the hypothesis in 1983, a substantial body of research has demonstrated that 568

Despite growing concerns about the quality and accuracy of Internet-based prescription drug information, there has been very little empirical research on consumers' perceptions of the trustworthiness of on-line drug information. In this article, we report on a study modeled after that of Menon, Deshpande, Perri, and Zinkhan (2002) in Health Marketing Quarterly that reexamines how key demographic, predispositional, and media factors are associated with consumer trust in on-line prescription drug information and the impact of trust in on-line drug information on ad-promoted behavior following exposure to direct-to-consumer (DTC) advertising. Four major findings are reported: (1) on-line drug information is not highly trusted; (2) trust in on-line drug information is not differentially affected by consumer demographic or predispositional characteristics; (3) trust in the traditional media of DTC advertising is predictive of trust in on-line drug information; and (4) trust in on-line drug information is associated directly with specific types of ad-promoted behavior following exposure to DTC advertising. Implications and recommendations are offered based on the results.

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