Objective: To investigate the influence level of activity of daily living about the patients about the Alzheimer's disease. Methods: Stratified multistage cluster sampling method to determine the survey, investigation and clinical diagnosis using two-stage screening method, screening stage using mini mental-mental state examination (MMSE) and activities of daily living (ADL), to test. According to the diagnostic phase of clinical history, clinical examination, neuropsychological testing to assess, diagnosis using DSM-Ⅳ and NINCDS-ADRDA criteria. On AD patients and normal elderly controls were assessed activities of daily living scale (ADL), evaluation and analysis of AD patients' daily living activities. Results: (1) The 3698 survey of 60-year-old and 60 years of age or older, the identified Alzheimer's disease (AD) patients with 87, Alzheimer's disease (AD) prevalence rate was 2.4%, which accounted for 59.77% of light; medium 24.14%; heavy accounted for 16.09%.(2) AD patients whose scores of activities of daily living, physical aspects and tools for self-care activities of daily living were significantly higher than normal (t = 8.02, P <0.01; t = 6.22, P <0.01; t = 8.15, P <0.01), two completely normal activities of daily living, decreased the rate of decline and the difference was statistically significant (χ2 = 24.09, P <0.01), description of daily living in patients with AD were lower; physical aspects of daily living score was significantly higher than tools for self-care activities of daily living score (t = 6.79, P <0.01), showed a more marked decline in physical function; patient groups of different age difference between the mean score of ADL was statistically significant (F = 5.49, P <0.01), showed ages, worse activities of daily living; patients groups of different severity difference between the mean score of ADL was statistically significant (F = 44.58, P <0.01), showed the more severe the disease, the more obvious activities of daily living impaired. Conclusion: Alzheimer's disease (AD) seriously affect the ability of daily life, AD patients with activities of daily living, physical aspects and tools for self-care activities of daily living were significantly lower, tools for self-care activities of damage was more obvious; the older, more serious disease, the more serious damage of daily living.