We report an intramolecular hydrogen bond-promoted Ugi cascade reaction for solvent-free synthesis of 2,5-diketopiperazines. Compounds (±) 5c and (±) 5e displayed potent antitumor activity against acute myeloid leukaemia and prostate cancer cell lines, respectively.
Correction for ‘An intramolecular hydrogen bond-promoted “green” Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity’ by Jie Li et al., RSC Adv., 2022, 12, 33175–33179, https://doi.org/10.1039/D2RA04958A.
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