A nickel(II)-catalyzed
oxygen transfer reaction of dibenzylideneacetone-derived N-vinyl-α,β-unsaturated nitrones has been identified
for the preparation of polysubstituted 2-(pyridin-2-yl)ethanols in
good yields with high atom economy. The scope of the method is described,
and mechanistic experiments are discussed. The reaction was easily
performed at gram scales, and pyrido[2,3-c]carbazole
was obtained in moderate yield over three steps.
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