Abstract. The Selenium-Polysaccharides from Rich selenium Chemical explicitly defined the Edible Fungus (Se-EF) in Boiling water extraction by alcohol precipitation, analysis indicated that the there were main ingredient comprises xylose, dextrose, rhamnose, galactose, and arabinose. First investigate lipids Metabolic and lipoprotein lipase (LPL) activated in the selenium-rich -EF rich in cholesterol and prospects by feeding rich foods (PRD). The purpose of this study is to explore the prospect 1st fed cholesterol-enriched diet (PRD) of KM mice selenium -EF on cholesterol metabolism and lipoprotein lipase (LPL) activated of antioxidant capacity. In addition, studies of the relationship between atherosclerosis and total antioxidant capacity index (AI) and LPL activity (TAC). The results showed that selenium polysaccharide significantly reduce TC serum total cholesterol and LDL-C concentrations comparatively in with the CK control groups. Furthermore, orally administered of polysaccharide selenium notable enhance pay, lipoprotein lipase activity and reduce MDA levels, and artificial intelligence. These results indicate that the beneficial affects of selenium on -EF hypercholesterolemia precautions. In addition, oral administration of polysaccharide selenium notable enhance TAC and LPL activity in the meantime reduce MDA levels, the same as AI. These results indicate that Se-EF has a beneficial effect on the prevention of hyperlipidemia. These results indicate that the beneficial affects of selenium on -EF hypercholesterolemia precautions.
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