Peripheral arterial disease (PAD) increases the risk of lower extremity amputation. It is also an independent predictor of cardiovascular and cerebrovascular ischemic events, affecting both the quality and expectancy of life. Many studies have demonstrated that the prevalence of PAD in patients with diabetes mellitus (DM) is higher than in non-diabetic patients. In diabetic patients, PAD occurs early with rapid progression, and is frequently asymptomatic. Multiple metabolic aberrations in DM, such as advanced glycation end-products, low-density lipoprotein cholesterol, and abnormal oxidative stress, have been shown to worsen PAD. However, the role of DM in PAD is not completely understood. The purpose of the present article is to review and discuss the pathophysiology of PAD in DM.

Objective: A large number of studies have shown the adverse neonatal outcomes of maternal psychological ill health. Given the potentially high prevalence of antenatal anxiety and few studies performed among Chinese people, the authors wanted to investigate the prevalence of antenatal anxiety and associated factors among pregnant women and to provide scientific basis to reduce prenatal anxiety effectively. Methods: A cross-sectional study was carried out at the Changchun Gynecology and Obstetrics Hospital from January 2015 to march 2015, with 467 participants of at least 38 weeks’ gestation enrolled. Antenatal anxiety was measured using the Self-Rating Anxiety Scale (SAS). χ2 test and logistic regression analysis were performed to evaluate the association of related factors of antenatal anxiety. Results: Among the 467 participants, the prevalence of antenatal anxiety was 20.6% (96 of 467). After adjustment for women’s socio-demographic characteristics (e.g., area, age, household income), multivariate logistical regression analysis revealed that antenatal anxiety showed significant relationship with education level lower than middle school (years ≤ 9), expected natural delivery, anemia during pregnancy, pregnancy-induced hypertension syndrome, disharmony in family relationship and life satisfaction. Conclusions: It is important to prevent or reduce antenatal anxiety from occurring by improving the health status of pregnant women and strengthening prenatal-related education and mental intervention.

The massive galaxy population above the characteristic Schechter mass M * ≈ 10 10.6 M contributes to about half of the total stellar mass in the local Universe. These massive galaxies usually reside in hot dark matter haloes above the critical shock-heating mass ∼10 12 M , where the external cold gas supply to these galaxies is expected to be suppressed. When galaxies run out of their cold gas reservoir, they become dead and quiescent. Therefore, massive quiescent galaxies living in hot haloes are commonly believed to be gas-poor. Based on the data from SDSS, ALFALFA, GASS and COLD GASS surveys, here we show that the vast majority of the massive, quiescent, central disk galaxies in the nearby Universe have a remarkably large amount of cold atomic hydrogen gas, surprisingly similar to starforming galaxies. Both star-forming and quiescent disk galaxies show identical symmetric double-horn H i spectra, indicating similar regularly rotating H i disks. Relative to their star-forming counterparts, massive quiescent central disk galaxies are quenched because of their significantly reduced molecular gas content, lower dust content, and lower star formation efficiency. Our findings reveal a new picture, which clearly demonstrates the detailed star-formation quenching process in massive galaxies and provides a stringent constraint on the physical mechanism of quenching.

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