As part of our screening of anticariogenic agents from medicinal plants, the ethanol extracts of 25 herbs widely used in the fork medicine were tested for the antimicrobial activity against a cariogenic bacterium Streptococcus mutans ATCC 25175. The ethanol extracts of Coptis chinensis, Sophora flavescens, Glycyrrhiza uralensis, Mentha arvensis, and Saururus chinensis showed antimicrobial activities against S. mutans. The extracts of Coptis chinensis and Sophora flavescens among these medicinal plants showed significant antomicrobial activity against S. mutans. These results suggested that the extracts of Coptis chinensis and Sophora flavescens could be the potential source of antimicrobial agent against S. mutans ATCC 25175.
키워드
Streptococcus mutans, 황련, 고삼
Pseudomonas aeruginosa에 대한 항균물질을 찾기 위하여 한의학에서 전통적으로 사용되어 오던 34종류 약용식 물로부터 에탄올 추출물들을 분리하여 항균활성을 조사하였다. Gardenia jasminoides, Arctium lappa, Citrus unshiu 및 Phellodendron amurense 등의 에탄올 추출물들이 P. aeruginosa ATCC 27853에 대해서 항균활성을 나타냈다. 이 들 중 Gardenia jasminoides의 에탄올 추출물은 P. aeruginosa에 대해 강한 항균활성을 나타냈다. 앞으로 이들 약용식 물들의 추출물들이 P. aeruginosa에 대한 천연항균물질로서 사용될 수 있을 것으로 기대된다.
ABSTRACTAnti-Pseudomonas aeruginosa activities for ethanol extract of 34 medicinal plants widely used in the folk medicine were evaluated to screening of anti-Pseudomonas aeruginosa agents. The ethanol extracts of Gardenia jasminoides, Arctium lappa, Citrus unshiu, and Phellodendron amurense showed antimicrobial activities against P. aeruginosa ATCC 27853. The ethanol extracts of Gardenia jasminoides among these medicinal plants showed significant antimicrobial activity against P. aeruginosa. Therefore, we expect that these medicinal plants will be useful for nature antimicrobial agent against P. aeruginosa in future.
키워드
Pseudomonas aeruginosa, 천연항균물질
Key wordPseudomonas aeruginosa, nature antimicrobial agent O pen Access http://dx
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